Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM50085497
Substrate
n/a
Meas. Tech.
ChEBML_156040
IC50
6200±n/a nM
Citation
 Lucas, R; Ubeda, A; Payá, M; Alves, M; del Olmo, E; López, JL; San Feliciano, A Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2. Bioorg Med Chem Lett 10:285-8 (2000) [PubMed]  Article 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM50085497
Synonyms:
2-(ethylamino)hexadecan-1-ol | 2-Ethylamino-hexadecan-1-ol | CHEMBL89206
Type:
Small organic molecule
Emp. Form.:
C18H39NO
Mol. Mass.:
285.5084
SMILES:
CCCCCCCCCCCCCCC(CO)NCC
Structure:
Search PDB for entries with ligand similarity: