Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50259759
Substrate
n/a
Meas. Tech.
ChEMBL_528821 (CHEMBL977663)
IC50
>150000±n/a nM
Citation
 Deng, S; Chen, SN; Yao, P; Nikolic, D; van Breemen, RB; Bolton, JL; Fong, HH; Farnsworth, NR; Pauli, GF Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. J Nat Prod 69:536-41 (2006) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50259759
Synonyms:
(S)-8-hydroxy-1-methoxy-, Z-9-heptadecene-4,6-diyn-3-one | CHEMBL479891
Type:
Small organic molecule
Emp. Form.:
C18H26O3
Mol. Mass.:
290.3972
SMILES:
CCCCCCC\C=C/[C@H](O)C#CC#CC(=O)CCOC |r|
Structure:
Search PDB for entries with ligand similarity: