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Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50304582
Substrate
n/a
Meas. Tech.
ChEMBL_605121 (CHEMBL1073935)
IC50
4504±n/a nM
Citation
 Fells, JI; Tsukahara, R; Liu, J; Tigyi, G; Parrill, AL Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem 17:7457-64 (2009) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:
Enzyme
Mol. Mass.:
40149.72
Organism:
Homo sapiens (Human)
Description:
Q9UBY5
Residue:
353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
  
Inhibitor
Name:
BDBM50304582
Synonyms:
CHEMBL610179 | [5-(3-nitrophenoxy)-1,3-dioxo-1,3-dihydro-2-isoindol-2-yl]acetic acid
Type:
Small organic molecule
Emp. Form.:
C16H10N2O7
Mol. Mass.:
342.2598
SMILES:
OC(=O)CN1C(=O)c2ccc(Oc3cccc(c3)[N+]([O-])=O)cc2C1=O
Structure:
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