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Target
Prostaglandin-H2 D-isomerase
Ligand
BDBM50009862
Substrate
n/a
Meas. Tech.
ChEMBL_158157 (CHEMBL877988)
IC50
570±n/a nM
Citation
 Bell, MR; D'Ambra, TE; Kumar, V; Eissenstat, MA; Herrmann, JL; Wetzel, JR; Rosi, D; Philion, RE; Daum, SJ; Hlasta, DJ Antinociceptive (aminoalkyl)indoles. J Med Chem 34:1099-110 (1991) [PubMed]  Article 
Target
Name:
Prostaglandin-H2 D-isomerase
Synonyms:
PTGDS_MOUSE | Ptgds
Type:
PROTEIN
Mol. Mass.:
21069.88
Organism:
Mus musculus
Description:
ChEMBL_158158
Residue:
189
Sequence:
MAALRMLWMGLVLLGLLGFPQTPAQGHDTVQPNFQQDKFLGRWYSAGLASNSSWFREKKAVLYMCKTVVAPSTEGGLNLTSTFLRKNQCETKIMVLQPAGAPGHYTYSSPHSGSIHSVSVVEANYDEYALLFSRGTKGPGQDFRMATLYSRTQTLKDELKEKFTTFSKAQGLTEEDIVFLPQPDKCIQE
  
Inhibitor
Name:
BDBM50009862
Synonyms:
CHEMBL12566 | {1-[2-(2-Hydroxy-morpholin-4-yl)-ethyl]-2-methyl-1H-indol-3-yl}-naphthalen-1-yl-methanone
Type:
Small organic molecule
Emp. Form.:
C26H26N2O3
Mol. Mass.:
414.4962
SMILES:
Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOC(O)C1
Structure:
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