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Target
Mu-type opioid receptor
Ligand
BDBM50036134
Substrate
n/a
Meas. Tech.
ChEMBL_145429 (CHEMBL748774)
Ki
206±n/a nM
Citation
 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE 7'-Substituted amino acid conjugates of naltrindole. Hydrophilic groups as determinants of selective antagonism of delta 1 opioid receptor-mediated antinociception in mice. J Med Chem 38:402-7 (1995) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50036134
Synonyms:
32+/-82-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-9-ylcarboxamido]acetic acid | CHEMBL422258
Type:
Small organic molecule
Emp. Form.:
C29H29N3O6
Mol. Mass.:
515.5571
SMILES:
OC(=O)CNC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67 |TLB:33:32:14:37.18.17,23:37:14:32.30.31,15:14:37.18.17:32.30.31,THB:13:14:37.18.17:32.30.31|
Structure:
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