Reaction Details Report a problem with these data
Target
Fe(3+)-pyochelin receptor
Ligand
BDBM50444962
Substrate
n/a
Meas. Tech.
ChEMBL_1281512 (CHEMBL3101970)
Ki
11±n/a nM
Citation
 Noël, S; Hoegy, F; Rivault, F; Rognan, D; Schalk, IJ; Mislin, GL Synthesis and biological properties of thiazole-analogues of pyochelin, a siderophore of Pseudomonas aeruginosa. Bioorg Med Chem Lett 24:132-5 (2013) [PubMed]  Article 
Target
Name:
Fe(3+)-pyochelin receptor
Synonyms:
FPTA_PSEAE | Fe(III)-pyochelin receptor | fptA
Type:
PROTEIN
Mol. Mass.:
79988.52
Organism:
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
Description:
ChEMBL_107982
Residue:
720
Sequence:
MKTETKVIKGRQGIARNRHTPLCLGLLLALSPLAAAVADARKDGETELPDMVISGESTSATQPPGVTTLGKVPLKPRELPQSASVIDHERLEQQNLFSLDEAMQQATGVTVQPFQLLTTAYYVRGFKVDSFELDGVPALLGNTASSPQDMAIYERVEILRGSNGLLHGTGNPAATVNLVRKRPQREFAASTTLSAGRWDRYRAEVDVGGPLSASGNVRGRAVAAYEDRDYFYDVADQGTRLLYGVTEFDLSPDTLLTVGAQYQHIDSITNMAGVPMAKDGSNLGLSRDTYLDVDWDRFKWDTYRAFGSLEQQLGGGWKGKVSAEYQEADSRLRYAGSFGAIDPQTGDGGQLMGAAYKFKSIQRSLDANLNGPVRLFGLTHELLGGVTYAQGETRQDTARFLNLPNTPVNVYRWDPHGVPRPQIGQYTSPGTTTTTQKGLYALGRIKLAEPLTLVVGGRESWWDQDTPATRFKPGRQFTPYGGLIWDFARDWSWYVSYAEVYQPQADRQTWNSEPLSPVEGKTYETGIKGELADGRLNLSLAAFRIDLENNPQEDPDHPGPPNNPFYISGGKVRSQGFELEGTGYLTPYWSLSAGYTYTSTEYLKDSQNDSGTRYSTFTPRHLLRLWSNYDLPWQDRRWSVGGGLQAQSDYSVDYRGVSMRQGGYALVNMRLGYKIDEHWTAAVNVNNLFDRTYYQSLSNPNWNNRYGEPRSFNVSLRGAF
  
Inhibitor
Name:
BDBM50444962
Synonyms:
CHEMBL3099909
Type:
Small organic molecule
Emp. Form.:
C14H15N3O3S2
Mol. Mass.:
337.417
SMILES:
CN1[C@@H](CSC1c1csc(n1)-c1ccc(N)cc1O)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: