TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:Competitive inhibition of AEP (unknown origin) using varying levels of Z-AAN-AMC substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 11.5nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibitory concentration of the compound was evaluated for Irreversible Inhibition of S. mansoni LegumainMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration of the compound was evaluated for Irreversible Inhibition of S. mansoni LegumainMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration of the compound was evaluated for Irreversible Inhibition of S. mansoni LegumainMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair