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TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536937BDBM50536937(CHEMBL4554200)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mouse recombinant PARP2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139658BDBM139658(US8894989, 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant PARP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27566BDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139658BDBM139658(US8894989, 37)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mouse recombinant PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27720BDBM27720(3-(4-chlorophenyl)quinoxaline-5-carboxamide | quin...)
Affinity DataIC50: 7nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27721BDBM27721(CHEMBL481603 | 3-(4-cyanophenyl)quinoxaline-5-carb...)
Affinity DataIC50: 8nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27723BDBM27723(CHEMBL519443 | 3-(4-methoxyphenyl)quinoxaline-5-ca...)
Affinity DataIC50: 8nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27724BDBM27724(3-(4-aminophenyl)quinoxaline-5-carboxamide | CHEMB...)
Affinity DataIC50: 9nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27722BDBM27722(CHEMBL521428 | 3-[4-(trifluoromethyl)phenyl]quinox...)
Affinity DataIC50: 11nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27719BDBM27719(3-phenylquinoxaline-5-carboxamide | quinoxaline an...)
Affinity DataIC50: 14nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27493BDBM27493(2-[4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl]-1,...)
Affinity DataIC50: 20nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27494BDBM27494(2-[4-(pyridin-2-yl)phenyl]-1,3-diazatricyclo[6.3.1...)
Affinity DataIC50: 28nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27498BDBM27498(4-Amino-1,8-naphthalimide | 10-amino-3-azatricyclo...)
Affinity DataIC50: 32nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27497BDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataIC50: 62nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27713BDBM27713(1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)buty...)
Affinity DataIC50: 70nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27714BDBM27714(CHEMBL361054 | 5-fluoro-1-[4-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 83nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27717BDBM27717(4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27718BDBM27718(CHEMBL194482 | 2-[3-(4-Phenyl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27707BDBM27707(CHEMBL481511 | 4-{1-[3-(8-chloro-4-oxo-3,4-dihydro...)
Affinity DataIC50: 87nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27716BDBM27716(4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]...)
Affinity DataIC50: 90nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341859BDBM50341859(2-(4-chlorophenyl)quinoxaline-5-carboxamide | CHEM...)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438603BDBM50438603(CHEMBL2414044)
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438601BDBM50438601(CHEMBL2414046)
Affinity DataIC50: 160nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27709BDBM27709(CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...)
Affinity DataIC50: 167nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438605BDBM50438605(CHEMBL2414042)
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27499BDBM27499(8-oxa-15-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]hep...)
Affinity DataIC50: 186nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438600BDBM50438600(CHEMBL2414048)
Affinity DataIC50: 260nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27711BDBM27711(2-{3-[4-(4-chlorophenyl)piperazin-1-yl]propyl}-3,4...)
Affinity DataIC50: 300nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27500BDBM27500(Phenanthridone | 5H-Phenanthridin-6-one (PTD) | 5H...)
Affinity DataIC50: 331nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27501BDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | isoquin...)
Affinity DataIC50: 447nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438604BDBM50438604(CHEMBL2414043)
Affinity DataIC50: 480nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27708BDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50: 500nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341860BDBM50341860(8-chloro-2-(4-(4-(4-fluorophenyl)-5,6-dihydropyrid...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341856BDBM50341856(5-(Carboxymethylamino)isoquinolin-1-one | CHEMBL17...)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27705BDBM27705(2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)prop...)
Affinity DataIC50: 608nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27706BDBM27706(CHEMBL251029 | 8-chloro-2-[3-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 610nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27710BDBM27710(5-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 630nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27712BDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50: 660nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438602BDBM50438602(CHEMBL2414045)
Affinity DataIC50: 730nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438599BDBM50438599(CHEMBL2414051)
Affinity DataIC50: 830nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27503BDBM27503(5-amino-1,2-dihydroisoquinolin-1-one | CHEMBL44624...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27503BDBM27503(5-amino-1,2-dihydroisoquinolin-1-one | CHEMBL44624...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27503BDBM27503(5-amino-1,2-dihydroisoquinolin-1-one | CHEMBL44624...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 138355BDBM138355(US8877944, P1)
Affinity DataKd:  1.05E+3nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341867BDBM50341867(5-(4-Iodobenzamido)isoquinolin-1-one | CHEMBL17670...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 39220BDBM39220((1-oxo-2H-isoquinolin-5-yl) benzoate | MLS00004277...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341861BDBM50341861(5-Benzamidoisoquinolin-1-one | CHEMBL1767054)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of mouse recombinant PARP-2 incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341861BDBM50341861(5-Benzamidoisoquinolin-1-one | CHEMBL1767054)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341857BDBM50341857(5-Amino-2-(2-carboxyethyl)isoquinolin-1-one | CHEM...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nirma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341863BDBM50341863(5-(4-Nitrobenzamido)isoquinolin-1-one | CHEMBL1767...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
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