Compile Data Set for Download or QSAR
Report error Found 414 of affinity data for UniProtKB/TrEMBL: P06935
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513893BDBM50513893(CHEMBL506092)
Affinity DataIC50: 56nMAssay Description:Inhibition of West Nile virus proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212337BDBM50212337(CHEMBL5267698)
Affinity DataKi:  69nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease using PhAc-Leu-LysLys-Arg-AMC as substrate measured for 10 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789691BDBM789691(((5-(trifluoromethyl)pyridin-3-yl)carbamoyl)(3-((5...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789692BDBM789692((3-((2'-methyl-[3,3'-bipyridin]-6-yl)methyl)-1,2,3...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789693BDBM789693((3-((4'-methyl-[3,3'-bipyridin]-6-yl)methyl)-1,2,3...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789629BDBM789629((R)-(3-(1-(4-(pyrimidin-5-yl)phenyl)ethyl)-1,2,3-o...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789689BDBM789689((3-((5-(4-methoxy-6-methylpyrimidin-5-yl)pyridin-2...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789573BDBM789573((3-(4-bromobenzyl)-1,2,3-oxadiazol-3-ium-5-yl)((3-...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789716BDBM789716((3-((5-(4-methylpyridazin-3-yl)pyridin-2-yl)methyl...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789628BDBM789628((S)-(3-(1-(4-(pyrimidin-5-yl)phenyl)ethyl)-1,2,3-o...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789688BDBM789688((3-((5-(2-methoxy-4-methylpyrimidin-5-yl)pyridin-2...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789683BDBM789683((3-((5-(5-methylpyridazin-4-yl)pyridin-2-yl)methyl...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789742BDBM789742((R)-(3-(1-(4-(4,6-dimethylpyrimidin-5-yl)phenyl)et...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789684BDBM789684((3-((5-(4,6-dimethylpyrimidin-5-yl)pyridin-2-yl)me...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789685BDBM789685(((3-(trifluoromethyl)phenyl)carbamoyl)(3-((5-(4-(t...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789714BDBM789714((3-((5-(pyridazin-4-yl)pyridin-2-yl)methyl)-1,2,3-...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789744BDBM789744((S)-(3-(1-(4-(4,6-dimethylpyrimidin-5-yl)phenyl)et...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789739BDBM789739((3-(4-(4,6-dimethylpyrimidin-5-yl)benzyl)-1,2,3-ox...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789618BDBM789618((3-(4-(2-hydroxypyridin-4-yl)benzyl)-1,2,3-oxadiaz...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789740BDBM789740((3-(4-(3,5-dimethylisoxazol-4-yl)benzyl)-1,2,3-oxa...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789615BDBM789615((3-(4-(pyridazin-4-yl)benzyl)-1,2,3-oxadiazol-3-iu...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789595BDBM789595((3-(4-(2-methoxypyrimidin-5-yl)benzyl)-1,2,3-oxadi...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789616BDBM789616((3-(4-(4-methoxypyrimidin-5-yl)benzyl)-1,2,3-oxadi...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789706BDBM789706((3-((5-(3,5-dimethylisoxazol-4-yl)pyridin-2-yl)met...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789680BDBM789680((3-((5-(3,5-dimethylisoxazol-4-yl)pyridin-2-yl)met...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789731BDBM789731(((2-(trifluoromethyl)pyridin-4-yl)carbamoyl)(3-((5...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789701BDBM789701(((5-(trifluoromethyl)pyridin-3-yl)carbamoyl)(3-((5...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789733BDBM789733((3-((5-(4-chloropyrimidin-5-yl)pyridin-2-yl)methyl...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789614BDBM789614((3-(4-(4-methylpyrimidin-5-yl)benzyl)-1,2,3-oxadia...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789702BDBM789702((3-((5-(4-cyanopyrimidin-5-yl)pyridin-2-yl)methyl)...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789734BDBM789734((3-((5-(4,6-dichloropyrimidin-5-yl)pyridin-2-yl)me...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789695BDBM789695((3-((2'-methyl-[3,3'-bipyridin]-6-yl)methyl)-1,2,3...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789727BDBM789727((3-((6-(3,5-dimethylisoxazol-4-yl)pyridazin-3-yl)m...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789697BDBM789697(((3-(trifluoromethyl)phenyl)carbamoyl)(3-((5-(1,3,...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789729BDBM789729((3-((5-(1,4-dimethyl-1H-pyrazol-5-yl)pyridin-2-yl)...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789611BDBM789611((3-(4-(pyrimidin-5-yl)benzyl)-1,2,3-oxadiazol-3-iu...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789698BDBM789698((3-((5-(4-cyanopyrimidin-5-yl)pyridin-2-yl)methyl)...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789730BDBM789730((3-((5-(4,6-dimethylpyrimidin-5-yl)pyridin-2-yl)me...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 789612BDBM789612((3-(4-(2-methoxypyrimidin-5-yl)benzyl)-1,2,3-oxadi...)
Affinity DataIC50: 100nMAssay Description:The enzyme inhibition assay was performed in 384-well flat bottom black polystyrene microplates (cat. N. 781900, Greiner,) in a reaction volume of 20...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35491BDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:Inhibition of West Nile virus NS2B (1393 to 1440 residues)-NS3 (1476 to 1687 residues) protease expressed in Escherichia coli BL21 (DE3) codon plus c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35491BDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35491BDBM35491(MLS000033898 | benzoic acid [5-amino-1-(4-methoxyp...)
Affinity DataIC50: 105nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35509BDBM35509(SMR000021572 | 2-thiophenecarboxylic acid [5-amino...)
Affinity DataIC50: 110nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35509BDBM35509(SMR000021572 | 2-thiophenecarboxylic acid [5-amino...)
Affinity DataIC50: 110nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212335BDBM50212335(CHEMBL5275144)
Affinity DataIC50: 120nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL21 (DE3) RILP codon plus competent cells using Benzoyl-NleKRR-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513894BDBM50513894(CHEMBL4457231)
Affinity DataKi:  120nMAssay Description:Inhibition of West Nile virus NS2B (47 residues)-NS3 (184 residues) protease expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567466BDBM50567466(CHEMBL4862682)
Affinity DataIC50: 120nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567466BDBM50567466(CHEMBL4862682)
Affinity DataIC50: 120nMAssay Description:Inhibition of West Nile virus NS2B (49 to 96 residues)-NS3 (2 to 184 residues) protease expressed in Escherichia coli BL21-rosetta cells using Bz-Nle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030459BDBM50030459(CHEMBL3344321)
Affinity DataKi:  130nMAssay Description:Inhibition of West Nile virus NS2B (52 to 96 residues)-NS3 (1 to 184 residues) protease using PhAc-Leu-LysLys-Arg-AMC3 TFA as substrate by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030459BDBM50030459(CHEMBL3344321)
Affinity DataKi:  130nMAssay Description:Inhibition of West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
Displayed 1 to 50 (of 414 total ) | Next | Last >>
Jump to: