BDBM50567466 CHEMBL4862682

SMILES NCc1ccc(cc1)-c1ncc(OCC2CCNCC2)nc1-c1ccc(cc1)-c1cn[nH]c1

InChI Key InChIKey=MYADMJMAENDCBG-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50567466   

TargetGenome polyprotein(Dengue virus 2)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50:  210nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNonstructural protein 3(Zika virus)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50:  760nMAssay Description:Inhibition Zika virus NS3B (47 to 95 residues)/NS3 (1 to 170 residues) protease expressed in Escherichia coli BL21 using 7-amino-4-methylcoumarin as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(Zika virus)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50:  710nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Charles University Prague

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Charles University Prague

Curated by ChEMBL
LigandPNGBDBM50567466(CHEMBL4862682)
Affinity DataIC50:  120nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed