Compile Data Set for Download or QSAR
Report error Found 650 of affinity data for UniProtKB/TrEMBL: P13631
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032223(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50: >0.00100nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032224(3-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50: >0.00100nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075367((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]RA binding to retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032218(5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50: >0.00100nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032225(5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50: >0.00100nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075366((2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cycl...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]RA binding to retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKi:  0.0400nMAssay Description:Agonistic activity towards retinoic acid receptor-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM323587(4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  0.0650nMAssay Description:Retinoid nuclear receptor activity is associated with transduction of the non-visual physiologic, pharmacologic, and toxicologic retinoid signals tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  0.200nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  0.200nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.200nMAssay Description:Activity at human RARgamma ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50457552(CHEMBL4210595)
Affinity DataEC50:  0.220nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  0.300nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  0.400nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50282692(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  0.400nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of [3H]RA to binding Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.5nMAssay Description:Transcriptional activation of retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]ATRA-Hl60 binding to Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075879(4-(2,2-Dimethyl-4-p-tolyl-2H-1-thia-anthracen-6-yl...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic activity against RAR gamma in transcriptional activation assay with 3.2 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.5nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM458152(US10752616, Code No. BHBA-010)
Affinity DataEC50:  0.530nMAssay Description:Transcriptional transactivation assays were performed with gal4 fusion receptor constructs, created using each of the RAR ligand binding domains of e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

LigandPNGBDBM31887(Ch 80 | BMS181156)
Affinity DataKd:  0.600nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50265920(4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  0.600nMAssay Description:Activity at human RARgamma ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataIC50: 0.620nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.700nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor gamma using transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  0.700nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKd:  0.800nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKd:  0.800nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM323588(Retinoic Acid | all-trans-retinoic acid | at-RA | ...)
Affinity DataEC50:  0.900nMAssay Description:Transcriptional transactivation assays were performed with gal4 fusion receptor constructs, created using each of the RAR ligand binding domains of e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50457563(CHEMBL4205733)
Affinity DataEC50:  0.920nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKi:  1nMAssay Description:Agonistic activity towards retinoic acid receptor-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50051553(6-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  1.30nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50282691(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  1.40nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50457554(CHEMBL4202830)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM31889(BMS 961 | BMS961 | BMS270394)
Affinity DataKi:  1.5nM ΔG°:  -46.8kJ/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50457560(CHEMBL3939687)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075878(4-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)...)
Affinity DataIC50: 2nMAssay Description:Antagonistic activity against RAR gamma in transcriptional activation assay with 3.2 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50048296(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-anthrace...)
Affinity DataKi:  2nMAssay Description:Binding affinity to retinoic acid receptor (RAR) gamma using [3H]CD 367 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075877(4-[5,5-Dimethyl-8-(5-methyl-thiophen-2-yl)-5,6-dih...)
Affinity DataIC50: 2nMAssay Description:Antagonistic activity against RAR gamma in transcriptional activation assay with 3.2 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50457546(CHEMBL4206237)
Affinity DataEC50:  2nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032219(4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  2nMAssay Description:Binding affinity against retinoic Acid gamma receptors co-transfected into CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50084832(4-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-quino...)
Affinity DataIC50: 2nMAssay Description:Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032219(4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  2nMAssay Description:Agonist activity for retinoic acid receptor RAR gamma in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032219(4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  2nMAssay Description:Transactivation potency for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50075880(4-(5,5-Dimethyl-8-p-tolyl-5,6-dihydro-anthracen-2-...)
Affinity DataIC50: 2nMAssay Description:Antagonistic activity against RAR gamma in transcriptional activation assay with 3.2 nM TTNPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50457561(CHEMBL3916016)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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