Compile Data Set for Download or QSAR
Report error Found 40 of affinity data for UniProtKB/TrEMBL: P15539
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238115BDBM50238115(CHEMBL4082403)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238115BDBM50238115(CHEMBL4082403)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238114BDBM50238114(CHEMBL4093575)
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645143BDBM50645143(CHEMBL5594758)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238115BDBM50238115(CHEMBL4082403)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238103BDBM50238103(CHEMBL4070323)
Affinity DataIC50: 102nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645141BDBM50645141(CHEMBL5570220)
Affinity DataIC50: 153nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238104BDBM50238104(CHEMBL4072871)
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8611BDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444549BDBM50444549(CHEMBL3099695)
Affinity DataIC50: 210nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238110BDBM50238110(CHEMBL4088766)
Affinity DataIC50: 257nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238105BDBM50238105(CHEMBL4099824)
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645142BDBM50645142(CHEMBL5575998)
Affinity DataIC50: 334nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238102BDBM50238102(CHEMBL4065476)
Affinity DataIC50: 440nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125049BDBM50125049(CHEMBL3623830)
Affinity DataIC50: 530nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645145BDBM50645145(CHEMBL5569999)
Affinity DataIC50: 761nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238109BDBM50238109(CHEMBL4091167)
Affinity DataIC50: 798nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238101BDBM50238101(CHEMBL4104118)
Affinity DataIC50: 911nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238106BDBM50238106(CHEMBL4072943)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238121BDBM50238121(CHEMBL4077051)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238108BDBM50238108(CHEMBL4070230)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238111BDBM50238111(CHEMBL4060559)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238119BDBM50238119(CHEMBL4075207)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238116BDBM50238116(CHEMBL4079006)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645144BDBM50645144(CHEMBL5575616)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238117BDBM50238117(CHEMBL4092081)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047262BDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047262BDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645146BDBM50645146(CHEMBL5568988)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238123BDBM50238123(CHEMBL4061565)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238112BDBM50238112(CHEMBL4101118)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645160BDBM50645160(CHEMBL5571493)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645150BDBM50645150(CHEMBL5572921)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645161BDBM50645161(CHEMBL5571637)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238113BDBM50238113(CHEMBL4067686)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645162BDBM50645162(CHEMBL5569452)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238107BDBM50238107(CHEMBL4064367)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125050BDBM50125050(CHEMBL3623831)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645147BDBM50645147(CHEMBL5595362)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645151BDBM50645151(CHEMBL5574189)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293-A cells using deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed