Compile Data Set for Download or QSAR
Report error Found 52 of affinity data for UniProtKB/TrEMBL: P16473
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614128BDBM50614128(CHEMBL5281228)
Affinity DataIC50: 11nMAssay Description:Allosteric antagonist activity at human TSHR expressed in CHO cells assessed as inhibition of bTSH-induced cAMP production incubated for 2 hrs by lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60862BDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 12nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614117BDBM50614117(CHEMBL5275472)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614127BDBM50614127(CHEMBL5267043)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614105BDBM50614105(CHEMBL5287707)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614120BDBM50614120(CHEMBL5267166)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614107BDBM50614107(CHEMBL5288869)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614110BDBM50614110(CHEMBL5270266)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 189329BDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614123BDBM50614123(CHEMBL5286556)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614106BDBM50614106(CHEMBL5275619)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614125BDBM50614125(CHEMBL5270771)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614109BDBM50614109(CHEMBL5285685)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614108BDBM50614108(CHEMBL5290721)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614104BDBM50614104(CHEMBL5283477)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614108BDBM50614108(CHEMBL5290721)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at human TSHR in HEK293 cells assessed as inhibition of bTSH-induced cAMP production incubated for 2 hrs by Eu-cAMP tracer based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614119BDBM50614119(CHEMBL5271120)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614111BDBM50614111(CHEMBL5279687)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614118BDBM50614118(CHEMBL5288635)
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614116BDBM50614116(CHEMBL5285143)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614115BDBM50614115(CHEMBL5285769)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614126BDBM50614126(CHEMBL5268829)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 189327BDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 88nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614114BDBM50614114(CHEMBL5268512)
Affinity DataIC50: 91nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60844BDBM60844(US9174940, 4)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60845BDBM60845(US9174940, 6)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60847BDBM60847(US9174940, 7)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60848BDBM60848(US9174940, 26 | US9174940, 11)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60843BDBM60843(US9174940, 1)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60853BDBM60853(US9174940, 27)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60855BDBM60855(US9174940, 28)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60856BDBM60856(US9174940, 29)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60857BDBM60857(US9174940, 30)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60849BDBM60849(US9174940, 12)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60850BDBM60850(US9174940, 13)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60851BDBM60851(US9174940, 18)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60848BDBM60848(US9174940, 26 | US9174940, 11)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60865BDBM60865(US9174940, 35)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60866BDBM60866(US9174940, 36)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60867BDBM60867(US9174940, 37)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60869BDBM60869(US9174940, 38)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60860BDBM60860(US9174940, 31)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60862BDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60863BDBM60863(US9174940, 33)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60864BDBM60864(US9174940, 34)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60870BDBM60870(US9174940, 39)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60872BDBM60872(US9174940, 40)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
US Patent

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614121BDBM50614121(CHEMBL5280508)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614122BDBM50614122(CHEMBL5273361)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614112BDBM50614112(CHEMBL5267037)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
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