Compile Data Set for Download or QSAR
Report error Found 1422 of affinity data for UniProtKB/TrEMBL: P21731
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035622BDBM50035622(l-Prostaglandin F2-alpha | (5Z,13E,15S)-9alpha,11a...)
Affinity DataIC50: 0.00100nMAssay Description:In vitro binding at TP human prostaglandin receptor using [3H]SQ-29,548 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026750BDBM50026750(CHEMBL3354618)
Affinity DataIC50: 0.0150nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047291BDBM50047291(3-(2-{3-[4-(6-Cyclohexyl-hexanoyl)-oxazol-2-yl]-7-...)
Affinity DataKd:  0.0500nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026748BDBM50026748(CHEMBL3354616)
Affinity DataIC50: 0.0520nMAssay Description:Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047266BDBM50047266(3-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.100nMAssay Description:Compound was evaluated for the receptor binding studies with Thromboxane A2 receptor using [3H]-SQ 29548 as radioligand in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047266BDBM50047266(3-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.100nMAssay Description:Dissociation constant was determined from radioligand binding studies in human platelet membranes using Thromboxane A2 receptor radioligand [3H]-SQ 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047266BDBM50047266(3-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.100nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060458BDBM50060458((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047278BDBM50047278(3-[2-(3-{4-[4-(4-Chloro-phenyl)-butylcarbamoyl]-ox...)
Affinity DataKd:  0.200nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047284BDBM50047284(3-{2-[3-(4-Heptylcarbamoyl-oxazol-2-yl)-7-oxa-bicy...)
Affinity DataKd:  0.200nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047300BDBM50047300(3-(2-{3-[4-(4-Phenyl-butylcarbamoyl)-oxazol-2-yl]-...)
Affinity DataKd:  0.300nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047270BDBM50047270(3-[2-(3-{4-[4-(4-Methoxy-phenyl)-butylcarbamoyl]-o...)
Affinity DataKd:  0.300nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50405907BDBM50405907(CHEMBL2096756)
Affinity DataKd:  0.400nMAssay Description:Compound was evaluated for inhibition of specific binding of HSQ (5,6-di-3H-SQ 29,548) in washed plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188618BDBM50188618(N-[2-(4-methylphenylamino)-5-nitrobenzenesulfonyl]...)
Affinity DataIC50: 0.460nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047280BDBM50047280(3-[2-(3-{4-[4-(4-Hydroxy-phenyl)-butylcarbamoyl]-o...)
Affinity DataKd:  0.5nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281917BDBM50281917(3-(2-{2-[4-(4-Chloro-benzylcarbamoyl)-oxazol-2-yl]...)
Affinity DataKd:  0.5nMAssay Description:Binding affinity was determined for Thromboxane A2 receptor in human platelet membrane using [3H]SQ-29,548 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188608BDBM50188608(N-tert-butyl-N'-[2-(2,6-dimethylphenylamino)-5-nit...)
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188613BDBM50188613(N-n-pentyl-N'-[2-(3-methyl-4-bromophenylamino)-5-n...)
Affinity DataIC50: 0.580nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161746BDBM50161746(CHEMBL361812 | 3-[(R)-3-(4-Fluoro-benzenesulfonyla...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to thromboxane receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047289BDBM50047289(3-(2-{3-[4-(5,5-Dimethyl-hexylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.600nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188615BDBM50188615(N-n-pentyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenes...)
Affinity DataIC50: 0.650nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188618BDBM50188618(N-[2-(4-methylphenylamino)-5-nitrobenzenesulfonyl]...)
Affinity DataIC50: 0.680nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188616BDBM50188616(N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitr...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047288BDBM50047288(3-(2-{3-[4-(2-Cyclohexyl-ethylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.700nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188622BDBM50188622(N-n-butyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047283BDBM50047283(3-{2-[3-(4-Phenethylcarbamoyl-oxazol-2-yl)-7-oxa-b...)
Affinity DataKd:  0.700nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188620BDBM50188620(N-n-hexyl-N'-[2-(cyclohexylamino)-5-nitrobenzenesu...)
Affinity DataIC50: 0.710nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188612BDBM50188612(N-n-hexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188622BDBM50188622(N-n-butyl-N'-[2-(4-methylphenoxy)-5-nitrobenzenesu...)
Affinity DataIC50: 0.740nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188623BDBM50188623(N-tert-butyl-N'-[2-(4-methylphenylthio)-5-nitroben...)
Affinity DataIC50: 0.770nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188619BDBM50188619(BM 573 | CHEMBL210602 | N-tert-butyl-N'-[2-(4-meth...)
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188608BDBM50188608(N-tert-butyl-N'-[2-(2,6-dimethylphenylamino)-5-nit...)
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188610BDBM50188610(N-cyclohexyl-N'-[2-(4-methylphenoxy)-5-nitrobenzen...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50188619BDBM50188619(BM 573 | CHEMBL210602 | N-tert-butyl-N'-[2-(4-meth...)
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047298BDBM50047298(3-(2-{3-[4-(1,1-Dimethyl-propylcarbamoyl)-oxazol-2...)
Affinity DataKd:  0.800nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205274BDBM50205274([(3R)-5-bromo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-...)
Affinity DataKi:  0.840nMAssay Description:Binding affinity to human TP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047294BDBM50047294(4-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.850nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002792BDBM50002792(CHEMBL431075 | 11-[2-(5-Benzylcarbamoyl-benzoimida...)
Affinity DataKi:  0.910nMAssay Description:Compound was tested for its binding affinity at Thromboxane A2/ Prostaglandin H2 receptor by measuring its ability to displace [3H]U-46619 from guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010073BDBM50010073(3-[2-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinoc...)
Affinity DataKd:  1nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047273BDBM50047273(2-{3-[2-(2-Carboxy-ethyl)-benzyl]-7-oxa-bicyclo[2....)
Affinity DataKd:  1nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391311BDBM50391311(CHEMBL352040)
Affinity DataKd:  1nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188607BDBM50188607(N-n-pentyl-N'-[2-(3-methylphenylamino)-5-nitrobenz...)
Affinity DataIC50: 1.01nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188619BDBM50188619(BM 573 | CHEMBL210602 | N-tert-butyl-N'-[2-(4-meth...)
Affinity DataIC50: 1.05nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188620BDBM50188620(N-n-hexyl-N'-[2-(cyclohexylamino)-5-nitrobenzenesu...)
Affinity DataIC50: 1.07nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188616BDBM50188616(N-n-pentyl-N'-[2-(3, 5-dimethylphenylamino)-5-nitr...)
Affinity DataIC50: 1.08nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188619BDBM50188619(BM 573 | CHEMBL210602 | N-tert-butyl-N'-[2-(4-meth...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015853BDBM50015853(CHEMBL310406 | 7-(3-{[2-(4-Cyclohexyl-butyrylamino...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098926BDBM50098926(1-(2-Cyclohexylamino-5-nitro-benzenesulfonyl)-3-pe...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory concentration of compound against thromboxane A2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188609BDBM50188609(N-benzyl-N'-[2-(4-methylphenylamino)-5-nitrobenzen...)
Affinity DataIC50: 1.17nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047303BDBM50047303((3-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-yl...)
Affinity DataKd:  1.20nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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