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TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 0.700nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in murine J774 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50: 3nMAssay Description:Inhibition of COX-1 in LPS-induced mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Mouse)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50229760(WAY-121520 | CHEMBL316184)
Affinity DataIC50: 4nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50474774(CHEMBL352430)
Affinity DataIC50: 71.2nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50: 87nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094535(1,3-diphenyl-4,7-dihydro-2H-isoindole | CHEMBL1408...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094540(1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094539(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094548(1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094555(5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094558(3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50293282(Imrecoxib | CHEMBL504535)
Affinity DataIC50: 114nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50293282(Imrecoxib | CHEMBL504535)
Affinity DataIC50: 115nMAssay Description:Inhibition of calcimycin-induced COX-1 in peritoneal macrophage of C57BL/J6 mouse assessed as 6-Keto prostaglandin F1alpha formation preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50474742(CHEMBL166295)
Affinity DataIC50: 177nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094551(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...)
Affinity DataIC50: 230nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094546(3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...)
Affinity DataIC50: 250nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094542(1,3-diphenyl-2,4,5,6-tetrahydrocyclopenta[c]pyrrol...)
Affinity DataIC50: 250nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094537(1-(4-Fluoro-phenyl)-3-(4-imidazol-1-yl-phenyl)-4,5...)
Affinity DataIC50: 500nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094547(1,3-bis(4-(methylthio)phenyl)-4,5,6,7-tetrahydro-2...)
Affinity DataIC50: 500nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094561(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 500nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094563(1,3-dip-tolyl-4,5,6,7-tetrahydro-2H-isoindole | 1,...)
Affinity DataIC50: 500nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50474765(CHEMBL353959)
Affinity DataIC50: 674nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50: 830nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094532(1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094538(CHEMBL554786 | CHEMBL522912 | 4,6-Diphenyl-1,2,3,5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094552(1,3-Diphenyl-benzo[c]thiophene | CHEMBL143653)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094553(CHEMBL552904 | CHEMBL496776 | 1,3-Bis-(4-imidazol-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094549(1,3-Bis-(4-methoxy-phenyl)-4,5,6,7-tetrahydro-2H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094528(5,6-Dimethyl-1,3-diphenyl-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094556(N-(1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindol-2-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094550(3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50361584(CHEMBL1939671)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX-1-mediated PGE2 production in arachidonic acid-stimulated mouse J774 cells incubated for 15 mins prior to arachidonic acid-challeng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50310340(3-(4-bromophenyl)-5-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50474770(CHEMBL353965)
Affinity DataIC50: 1.99E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094536(1,3-Diphenyl-2,3-dihydro-1H-isoindole | CHEMBL1412...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094559(1,3-Diphenyl-2,3-dihydro-1H-isoindole | CHEMBL1400...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094557(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizine | CHEMBL34...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50430956(CHEMBL2337405)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of arachidonic acid-induced COX1 activity in mouse J774 cells assessed as decrease in PGE2 levels incubated for 15 mins prior to arachidon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50361595(CHEMBL1939514 | US9162979, 5-II)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of COX-1-mediated PGE2 production in arachidonic acid-stimulated mouse J774 cells incubated for 15 mins prior to arachidonic acid-challeng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of COX1 in arachidonic acid-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50430950(CHEMBL2337398 | US9162979, 42-II)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of arachidonic acid-induced COX1 activity in mouse J774 cells assessed as decrease in PGE2 levels incubated for 15 mins prior to arachidon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of PGE2 production incubated for 15 mins prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of COX-1-mediated PGE2 production in arachidonic acid-stimulated mouse J774 cells incubated for 15 mins prior to arachidonic acid-challeng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
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