Compile Data Set for Download or QSAR
Report error Found 34 of affinity data for UniProtKB/TrEMBL: P22888
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206401BDBM50206401(N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataKi:  0.311nMAssay Description:Displacement of [125I]hCG from LH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335467BDBM50335467(5-amino-N-tert-butyl-2-(methylthio)-4-(3-(2-oxo-2-...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335473BDBM50335473(5-amino-4-(3-(2-((1-(2-(2-(2-azidoethoxy)ethoxy)et...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335468BDBM50335468((R)-4-(3-(2-((1-(2-(4-((4-(1-acetyl-6-biphenyl-4-y...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206401BDBM50206401(N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335474BDBM50335474((S)-4-(3-(2-((1-(2-(4-((4-(1-acetyl-6-biphenyl-4-y...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335469BDBM50335469((R)-4-(3-(2-((1-(2-(2-(4-((4-(1-acetyl-6-biphenyl-...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335478BDBM50335478((S)-4-(3-(2-((1-(14-(4-((4-(1-acetyl-6-biphenyl-4-...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335470BDBM50335470((R)-4-(3-(2-((1-(2-(2-(2-(4-((4-(1-acetyl-6-biphen...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335472BDBM50335472((R)-4-(3-(2-((1-(14-(4-((4-(1-acetyl-6-biphenyl-4-...)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335477BDBM50335477((S)-4-(3-(2-((1-(2-(2-(2-(2-(4-((4-(1-acetyl-6-bip...)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335471BDBM50335471((R)-4-(3-(2-((1-(2-(2-(2-(2-(4-((4-(1-acetyl-6-bip...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335476BDBM50335476((S)-4-(3-(2-((1-(2-(2-(2-(4-((4-(1-acetyl-6-biphen...)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206398BDBM50206398(N-(4-hydroxyphenethyl)-5-(1-(4-tert-butylphenyl)-3...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335475BDBM50335475((S)-4-(3-(2-((1-(2-(2-(4-((4-(1-acetyl-6-biphenyl-...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206402BDBM50206402(N-((S)-1-amino-3-(3-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206399BDBM50206399(N-((S)-2-amino-1-(4-hydroxyphenyl)-2-oxoethyl)-6-(...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206397BDBM50206397((S)-N-(4-amino-4-oxo-1-phenylbutan-2-yl)-5-(1-(4-t...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189778BDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at LHCGR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206395BDBM50206395((S)-N-(1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189778BDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206400BDBM50206400(N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189779BDBM50189779(N-tert-butyl-5-amino-4-(3-methoxyphenyl)-N-methyl-...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189775BDBM50189775(N-tert-butyl-5-amino-4-(2,3-dimethoxyphenyl)-2-(me...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189776BDBM50189776(tert-butyl 5-amino-4-(3-methoxyphenyl)-2-(methylth...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189777BDBM50189777(N-tert-butyl-5-amino-4-(3-fluorophenyl)-2-(methylt...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189773BDBM50189773(N-tert-butyl-5-amino-4-(2-fluoro-3-methoxyphenyl)-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256858BDBM50256858(Cyclopentyl-carbamic acid [1,1',3',1'']terphenyl-5...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human luteinizing hormone receptor expressed in CHOK1 cells assessed as c-AMP-mediated luciferase productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189774BDBM50189774(N-tert-butyl-5-amino-4-(3-hydroxyphenyl)-2-(methyl...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256858BDBM50256858(Cyclopentyl-carbamic acid [1,1',3',1'']terphenyl-5...)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]Org43553 from human luteinizing hormone receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206405BDBM50206405((S)-N-(1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206403BDBM50206403(N-((S)-1-amino-3-(4-tert-butoxyphenyl)-1-oxopropan...)
Affinity DataEC50:  1.21E+4nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206396BDBM50206396((S)-2-{3-[2-(4-tert-butyl-phenyl)-5-pyridin-3-yl-2...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206404BDBM50206404((S)-N-(1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed