Affinity DataEC50: 1nMAssay Description:Allosteric activation of human FSH receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay.More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 8.90nMAssay Description:Agonistic activity against human follicle stimulating hormone receptor in CHO-hFSHR-luciferase assay.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of maximum response evoked by cAMP on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Allosteric antagonist activity at human FSHR expressed in CHO cells assessed as inhibition of FSH-induced activity incubated for 4 hrs by CRE-lucifer...More data for this Ligand-Target Pair
TargetFollicle-stimulating hormone receptor(Homo sapiens)
Shanghai Institute of Materia Medica
Curated by ChEMBL
Shanghai Institute of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human FSH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human FSH receptor by aromatase-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at human FSH receptor by cAMP-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunoss...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF a...More data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 214nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:In vitro inhibition of maximum response on CHO-K1 cells expressing human Follicle stimulating hormone receptorMore data for this Ligand-Target Pair
TargetFollicle-stimulating hormone receptor(Homo sapiens)
Shanghai Institute of Materia Medica
Curated by ChEMBL
Shanghai Institute of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 259nMAssay Description:Inhibition of human FSH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Agonistic activity against Follicle stimulating hormone receptor expressed in chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataIC50: 322nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
TargetFollicle-stimulating hormone receptor(Homo sapiens)
Shanghai Institute of Materia Medica
Curated by ChEMBL
Shanghai Institute of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 322nMAssay Description:Inhibition of human FSH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataEC50: 397nMAssay Description:Agonist activity at human FSHR receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 432nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataIC50: 449nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Affinity DataIC50: 458nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair









































