Compile Data Set for Download or QSAR
Report error Found 21 of affinity data for UniProtKB/TrEMBL: P24527
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425166BDBM50425166(CHEMBL2313573)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425170BDBM50425170(CHEMBL2313569)
Affinity DataIC50: 17nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425148BDBM50425148(CHEMBL2313566)
Affinity DataIC50: 19nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425164BDBM50425164(CHEMBL2313265)
Affinity DataIC50: 21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425168BDBM50425168(CHEMBL2313571)
Affinity DataIC50: 21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425157BDBM50425157(CHEMBL2313272)
Affinity DataIC50: 21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425151BDBM50425151(CHEMBL2313563)
Affinity DataIC50: 21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425163BDBM50425163(CHEMBL2313266)
Affinity DataIC50: 27nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425149BDBM50425149(CHEMBL2313565)
Affinity DataIC50: 49nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425167BDBM50425167(CHEMBL2313572)
Affinity DataIC50: 69nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425153BDBM50425153(CHEMBL2313561)
Affinity DataIC50: 91nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425171BDBM50425171(CHEMBL2313568)
Affinity DataIC50: 100nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425152BDBM50425152(CHEMBL2313562)
Affinity DataIC50: 140nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425160BDBM50425160(CHEMBL2313269)
Affinity DataIC50: 210nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425169BDBM50425169(CHEMBL2313570)
Affinity DataIC50: 230nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425165BDBM50425165(CHEMBL2313264)
Affinity DataIC50: 250nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425147BDBM50425147(CHEMBL2313567)
Affinity DataIC50: 280nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425154BDBM50425154(CHEMBL2313560)
Affinity DataIC50: 420nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50082665BDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 790nMAssay Description:Inhibition of LTA4H in C57BL/6 mouse assessed as reduction in LTB4 production pre-incubated for 30 mins before 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425150BDBM50425150(CHEMBL2313564)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of LTA4H in C57BL/6 mouse assessed as reduction in LTB4 production pre-incubated for 30 mins before 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)