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Found 2 Enz. Inhib. hit(s) with Target = 'Leukotriene A-4 hydrolase' and Ligand = 'BDBM50425167'
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425167(CHEMBL2313572)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425167(CHEMBL2313572)
Affinity DataIC50:  69nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed