Compile Data Set for Download or QSAR
Report error Found 500 for UniProtKB: P28702
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50490451(CHEMBL2325917)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at RXR (unknown origin) in presence of RAR agonist Am80More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50490452(CHEMBL2321917)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at RXR (unknown origin) in presence of RAR agonist Am80More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at full length human RXR beta expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50101445(3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,...)
Affinity DataEC50:  0.800nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at full length human RXR beta expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataEC50:  2nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor beta using transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052588((2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,...)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]-Targretin binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135461((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3',5'-difluo...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataKd:  2.5nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataKd:  2.5nMAssay Description:Inhibition of [3H]9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataEC50:  2.60nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50285919(2-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  3nMAssay Description:Agonist activity for retinoic acid receptor RXR beta in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50101445(3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,...)
Affinity DataKd:  3.60nMAssay Description:Inhibition of [3H]9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKi:  3.80nMAssay Description:Agonistic activity towards retinoid X receptor-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135460((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-4'-fluoro-5-...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135453((2E,4E,6Z)-7-[2-(2,2-Difluoro-ethoxy)-3-isopropyl-...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50129720(7-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-pheny...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50141600((Z)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]9-cis-RA from Retinoic X receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50290660((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]9-cis-RA binding to RXR beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataEC50:  4.5nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50074300(4-[[(E)-Hydroxyimino]-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards recombinantly expressed Retinoic acid receptor RXR-beta in baculoviral system, by using 5 nM [3H]targretin in a competitive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135457((2E,4E,6E)-7-[2-(2,2-Difluoro-ethoxy)-3,5-bis-(1,1...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKi:  5.90nMAssay Description:Selective activity towards retinoid X receptor-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50074304(4-{(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards recombinantly expressed Retinoic acid receptor RXR-beta in baculoviral system, by using 5 nM [3H]targretin in a competitive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human RXR-beta expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50290659((2E,4E)-3-Methyl-5-[1-(5,5,8,8-tetramethyl-5,6,7,8...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]9-cis-RA binding to RXR beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135462((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-3'-fluoro-5-...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50032671(6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-nap...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]9-cis-RA from Retinoic X receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50533809(CHEMBL4547228)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50074295(4-[[(E)-Methoxyimino]-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataKi:  8nMAssay Description:Binding affinity towards recombinantly expressed Retinoic acid receptor RXR-beta in baculoviral system, by using 5 nM [3H]targretin in a competitive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052588((2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,...)
Affinity DataEC50:  8nMAssay Description:Transcriptional activation of Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135456((2E,4E,6Z)-7-(2-Butoxy-3-isopropyl-5-pentafluoroet...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135451((2E,4E,6Z)-7-(2-Ethoxy-3-isopropyl-5-pentafluoroet...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052590((2E,4E,6Z)-7-(3-Ethoxy-5,5,8,8-tetramethyl-5,6,7,8...)
Affinity DataEC50:  9nMAssay Description:Transcriptional activation of Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]-Targretin binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052589((2E,4E,6Z)-3-Methyl-7-(5,5,8,8-tetramethyl-3-propo...)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]-Targretin binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50135455((2E,4E,6Z)-7-(5-Isopropyl-3-pentafluoroethyl-2-pro...)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50074295(4-[[(E)-Methoxyimino]-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataEC50:  10nMAssay Description:Transcriptional activity was evaluated in CV-1 cells transfected with expression vector for Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50141599((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2,2-trifluoro-eth...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]9-cis-RA from Retinoic X receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50141595((E)-3-{4-[3,5-Di-tert-butyl-2-(3-fluoro-propoxy)-p...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]9-cis-RA from Retinoic X receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052033((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...)
Affinity DataKi:  10.2nMAssay Description:Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052033((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...)
Affinity DataKi:  10.2nMAssay Description:Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataKd:  11nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50141590((E)-3-[4-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]9-cis-RA from Retinoic X receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50052590((2E,4E,6Z)-7-(3-Ethoxy-5,5,8,8-tetramethyl-5,6,7,8...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]-Targretin binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM31892(CHEMBL705 | 9-cis retinoic acid | alitretinoin | P...)
Affinity DataIC50: 12nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50074299(4-[[(E)-Ethoxyimino]-(3,5,5,8,8-pentamethyl-5,6,7,...)
Affinity DataEC50:  12nMAssay Description:Transcriptional activity was evaluated in CV-1 cells transfected with expression vector for Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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