Compile Data Set for Download or QSAR
Report error Found 37 of affinity data for UniProtKB/TrEMBL: P41972
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471296BDBM50471296(CHEMBL87935)
Affinity DataIC50: 0.700nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataIC50: 0.850nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471292BDBM50471292(CHEMBL315230)
Affinity DataIC50: 1.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471294BDBM50471294(CHEMBL276855)
Affinity DataIC50: 1.90nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471297BDBM50471297(CHEMBL424608)
Affinity DataIC50: 2.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471293BDBM50471293(CHEMBL83449)
Affinity DataIC50: 3.60nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470911BDBM50470911(CHEMBL122825)
Affinity DataIC50: 4.45nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471295BDBM50471295(CHEMBL312853)
Affinity DataIC50: 5.30nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471291BDBM50471291(CHEMBL83394)
Affinity DataIC50: 6nMAssay Description:Inhibition concentration against isoleucyl tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470914BDBM50470914(CHEMBL120343)
Affinity DataIC50: 6.67nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus NCTC 3571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470913BDBM50470913(CHEMBL120798)
Affinity DataIC50: 6.87nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470912BDBM50470912(CHEMBL120437)
Affinity DataIC50: 7.98nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093003BDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093001BDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075056BDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075058BDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 50nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075067BDBM50075067(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 54nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093004BDBM50093004((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075069BDBM50075069(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 90nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075055BDBM50075055(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075063BDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093002BDBM50093002((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50: 120nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075065BDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 120nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075061BDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 130nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075062BDBM50075062(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 240nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470914BDBM50470914(CHEMBL120343)
Affinity DataIC50: 242nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus 11481More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075070BDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 270nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataIC50: 279nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus 11481More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075059BDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 300nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093005BDBM50093005((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...)
Affinity DataIC50: 910nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093008BDBM50093008((4aR,6S,7R,7aS)-4-Carbamoyl-6-hydroxy-2-methyl-7-[...)
Affinity DataIC50: 3.27E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075068BDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)
Affinity DataIC50: 8.00E+3nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093007BDBM50093007((4aR,6S,7R,7aS)-4-Carbamoyl-2-methyl-6-((S)-3-meth...)
Affinity DataIC50: 1.46E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus C 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470915BDBM50470915(CHEMBL118698)
Affinity DataIC50: 8.35E+5nMAssay Description:compound was tested for inhibitory activity of isoleucyl-tRNA synthetase (IRS). More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470915BDBM50470915(CHEMBL118698)
Affinity DataIC50: 8.35E+5nMAssay Description:compound was tested for inhibitory activity of isoleucyl-tRNA synthetase (IRS). More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470915BDBM50470915(CHEMBL118698)
Affinity DataIC50: 8.35E+5nMAssay Description:compound was tested for inhibitory activity of isoleucyl-tRNA synthetase (IRS). More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed