Compile Data Set for Download or QSAR
Report error Found 127 of affinity data for UniProtKB/TrEMBL: P48776
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289137BDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289138BDBM50289138(3-((E)-2-Pyridin-3-yl-vinyl)-1H-indole | CHEMBL441...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350293BDBM50350293(CHEMBL1812539)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289137BDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of mouse TDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350248BDBM50350248(CHEMBL1812545)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of mouse TDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350298BDBM50350298(CHEMBL1812546)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350248BDBM50350248(CHEMBL1812545)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350285BDBM50350285(CHEMBL1812531)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289136BDBM50289136(6-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350249BDBM50350249(CHEMBL1812547)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350294BDBM50350294(CHEMBL1812540)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350296BDBM50350296(CHEMBL1812543)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051818BDBM50051818(CHEMBL3318333)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells using L-tryptophan substrate incubated for 24 hrs by HPLC based cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289140BDBM50289140(5-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32142BDBM32142(cid_416002 | 5-amino-8-quinolinol | AS-0308-225 | ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514753BDBM50514753(CHEMBL4557994)
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of mouse TDO transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350240BDBM50350240(CHEMBL1812554)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303906BDBM50303906((E)-4-(isopropylimino)-2-methylnaphthalen-1(4H)-on...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350262BDBM50350262(CHEMBL1812506)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350289BDBM50350289(CHEMBL1812535)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350292BDBM50350292(CHEMBL1812538)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350297BDBM50350297(CHEMBL1812544)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303901BDBM50303901(1,4-Dihydroxynaphthalene | 1,4-Naphthohydroquinone...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350308BDBM50350308(CHEMBL1812541)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514760BDBM50514760(CHEMBL4448402)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of mouse TDO transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303903BDBM50303903(4-(Isopropylamino)-1-naphthol | CHEMBL578212)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350248BDBM50350248(CHEMBL1812545)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350299BDBM50350299(CHEMBL445966)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350254BDBM50350254(CHEMBL1812498)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289142BDBM50289142(3-((E)-2-Pyridin-4-yl-vinyl)-1H-indole | CHEMBL166...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350275BDBM50350275(CHEMBL1812520)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350267BDBM50350267(CHEMBL1812512)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350282BDBM50350282(CHEMBL1812528)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289139BDBM50289139(3-((E)-2-Pyridin-2-yl-vinyl)-1H-indole | CHEMBL171...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514752BDBM50514752(CHEMBL4458549)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of mouse TDO transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350263BDBM50350263(CHEMBL1812507)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350287BDBM50350287(CHEMBL1812533)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350268BDBM50350268(CHEMBL1812513)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350270BDBM50350270(CHEMBL1812515)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350243BDBM50350243(CHEMBL176991)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303902BDBM50303902(4-(ethylamino)naphthalen-1-ol | CHEMBL577335)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303904BDBM50303904((4E,4'E)-4,4'-bis(isopropylimino)-4',4'a-dihydro-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303905BDBM50303905((4E,4'E)-4,4'-bis(pentan-3-ylimino)-4',4'a-dihydro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 310197BDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 310195BDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 309529BDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350307BDBM50350307(CHEMBL1812526)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300305BDBM50300305(4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350247BDBM50350247(CHEMBL1812659)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350246BDBM50350246(CHEMBL1812658)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
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