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Report error Found 1730 for UniProtKB: P49286
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230659(CHEMBL37549)
Affinity DataIC50: 0.0000500nMAssay Description:Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50470001(CHEMBL322339)
Affinity DataKd:  0.000270nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50408578(CHEMBL417151)
Affinity DataKd:  0.000418nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230659(CHEMBL37549)
Affinity DataKd:  0.000453nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50315177(N-(3-(2-(benzyloxy)-5-methoxyphenyl)propyl)propion...)
Affinity DataKi:  0.000550nMAssay Description:Displacement of [3H]melatonin from human melatonin MT2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50315171(N-(3-(5-methoxy-2-(3-methoxybenzyloxy)phenyl)propy...)
Affinity DataKi:  0.000690nMAssay Description:Displacement of [3H]melatonin from human melatonin MT2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50470007(CHEMBL322269)
Affinity DataKd:  0.000800nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50266433(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  0.00100nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50470001(CHEMBL322339)
Affinity DataIC50: 0.00100nMAssay Description:Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50315178(N-(3-(2-(benzyloxy)-5-methoxyphenyl)propyl)butyram...)
Affinity DataKi:  0.00103nMAssay Description:Displacement of [3H]melatonin from human melatonin MT2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50470007(CHEMBL322269)
Affinity DataIC50: 0.00118nMAssay Description:Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230663(CHEMBL34349)
Affinity DataKd:  0.00343nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230657(CHEMBL290493)
Affinity DataIC50: 0.00345nMAssay Description:Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM29611(CHEMBL289233 | Melatonin,2-Iodo | 2-Iodomelatonin)
Affinity DataIC50: 0.00500nMAssay Description:Inhibition of 2-[125I]iodomelatonin stimulated calcium dependent dopamine release from the rabbit retina.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2019
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343590(N-{2-[7-(1-Benzothien-3-yl)-1,6-dihydro-2H-indeno[...)
Affinity DataKi:  0.00600nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50118462(2,2,2-Trifluoro-N-[2-(6-methoxy-2-phenyl-3H-inden-...)
Affinity DataKi:  0.00602nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to human melatonin receptor type 1A (MT1) expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230657(CHEMBL290493)
Affinity DataKd:  0.00615nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343599(N-[2-(7-Phenyl-1,6-dihydro-2H-indeno[5,4-b]furan-8...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343599(N-[2-(7-Phenyl-1,6-dihydro-2H-indeno[5,4-b]furan-8...)
Affinity DataKi:  0.00650nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343601(N-{2-[7-(3-Thienylmethyl)-1,6-dihydro-2H-indeno[5,...)
Affinity DataKi:  0.00670nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343603(N-[2-(7-Benzyl-1,6-dihydro-2H-indeno[5,4-b]furan-8...)
Affinity DataKi:  0.00850nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343595(N-{2-[7-(3-Methoxyphenyl)-1,6-dihydro-2H-indeno[5,...)
Affinity DataKi:  0.00900nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343598(N-{2-[7-(3-Furyl)-1,6-dihydro-2H-indeno[5,4-b]fura...)
Affinity DataKi:  0.00960nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343605(2,2,2-Trifluoro-N-[2-(7-isopropyl-1,6-dihydro-2H-i...)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114725(N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-a...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]iodomelatonin as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50637171(CHEMBL5555481)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to human MT2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50231291(CHEMBL421013)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of 2-[125I]iodomelatonin stimulated calcium dependent dopamine release from the rabbit retina.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2019
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM29611(CHEMBL289233 | Melatonin,2-Iodo | 2-Iodomelatonin)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343607(N-[2-(7-Isopropyl-1,6-dihydro-2H-indeno[5,4-b]fura...)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343592(N-{2-[7-(3-Isopropylphenyl)-1,6-dihydro-2H-indeno[...)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343602(N-{2-[7-(Cyclohexylmethyl)-1,6-dihydro-2H-indeno[5...)
Affinity DataKi:  0.0120nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50118435(2,2,2-Trifluoro-N-[2-(6-methoxy-indan-1-yl)-ethyl]...)
Affinity DataKi:  0.0123nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to human melatonin receptor type 1A (MT1) expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343600(N-[2-(7-Bromo-1,6-dihydro-2H-indeno[5,4-b]furan-8-...)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50471134(CHEMBL64664)
Affinity DataKi:  0.0140nMAssay Description:Displacement of 2-[125I]iodomelatonin from melatonin receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50471125(CHEMBL433237)
Affinity DataKi:  0.0140nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin (100 pM) as labelled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469993(CHEMBL320267)
Affinity DataIC50: 0.0153nMAssay Description:Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50470004(CHEMBL111458)
Affinity DataKd:  0.0155nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50240440(CHEMBL285718 | 4-P-PDOT | N-(4-Phenyl-1,2,3,4-tetr...)
Affinity DataKi:  0.0158nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human melatonin receptor MT2 expressed in NIH3T3 rat fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469993(CHEMBL320267)
Affinity DataKd:  0.0164nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50034110(Melatonin,2-Phenyl | CHEMBL15060 | N-[2-(5-Methoxy...)
Affinity DataKi:  0.0170nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin (100 pM) as labelled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50034110(Melatonin,2-Phenyl | CHEMBL15060 | N-[2-(5-Methoxy...)
Affinity DataKi:  0.0170nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataIC50: 0.0170nMAssay Description:Inhibition of 2-[125I]iodomelatonin stimulated calcium dependent dopamine release from the rabbit retina.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2019
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343608(N-[2-(7-Isopropyl-1,6-dihydro-2H-indeno[5,4-b]fura...)
Affinity DataKi:  0.0180nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114703(N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-a...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]iodomelatonin as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343596(N-{2-[7-(2-Methoxyphenyl)-1,6-dihydro-2H-indeno[5,...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50117920(CHEMBL3612471)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to human MT2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114703(N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-a...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of 2-[125I]Iodomelatonin from human MT2 melatonin receptor expressed in HEK cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50114718(But-3-enoic acid [2-(5-methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]iodomelatonin as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM29611(CHEMBL289233 | Melatonin,2-Iodo | 2-Iodomelatonin)
Affinity DataKi:  0.0210nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to melatonin receptor in quail brain as 1/KaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50408556(CHEMBL37771)
Affinity DataKd:  0.0219nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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