Compile Data Set for Download or QSAR
Report error Found 19 of affinity data for UniProtKB/TrEMBL: P50454
TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50162505(6-Chloro-2-oxo-2,3-dihydro-2lambda*4*-benzo[1,2,3]...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against Hsp47 collagen chaperone in turbidity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769537((3,5-dibromo-4-hydroxyphenyl)(2,7-diethylbenzofura...)
Affinity DataEC50:  5.52E+3nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50162506(2-[2-(4-Chloro-3-methyl-phenyl)-2-oxo-ethylsulfany...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory concentration against Hsp47 collagen chaperone in turbidity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769528((7-chloro-2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-di...)
Affinity DataEC50:  1.59E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50162504(4-[1-(4-Fluoro-phenyl)-2-nitro-ethylsulfanyl]-phen...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibitory concentration against Hsp47 collagen chaperone in turbidity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50162507(4-[1-(4-Methoxy-phenyl)-2-nitro-ethylsulfanyl]-phe...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibitory concentration against Hsp47 collagen chaperone in turbidity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769532(benzofuran-3-yl(3,5-dibromo-4-hydroxyphenyl)methan...)
Affinity DataEC50:  3.14E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769538((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-(trifluoro...)
Affinity DataEC50:  3.21E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769523((2-ethyl-5-methylbenzofuran-3-yl)(4-hydroxy-3,5-di...)
Affinity DataEC50:  3.71E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769520((7-chloro-2-ethylbenzofuran-3-yl)(3,5-dibromo-4-hy...)
Affinity DataEC50:  3.78E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769517((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-5-methylbenz...)
Affinity DataEC50:  4.08E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769531((7-bromo-2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-dii...)
Affinity DataEC50:  4.83E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769526((2-ethyl-7-methylbenzofuran-3-yl)(4-hydroxy-3,5-di...)
Affinity DataEC50:  4.91E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769535((3,5-dibromo-4-hydroxyphenyl)(2,5-diethylbenzofura...)
Affinity DataEC50:  4.92E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769539((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-4-methylbenz...)
Affinity DataEC50:  7.10E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769518((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-7-methylbenz...)
Affinity DataEC50:  7.30E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769524((6-chloro-2-ethylbenzofuran-3-yl)(3,5-dibromo-4-hy...)
Affinity DataEC50:  7.31E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769522((7-bromo-2-ethylbenzofuran-3-yl)(3,5-dibromo-4-hyd...)
Affinity DataEC50:  8.08E+4nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetSerpin H1(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM769541((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-4-fluorobenz...)
Affinity DataEC50:  1.05E+5nMAssay Description:Fibrils were formed by adding 180 ul of phosphate-buffered saline (PBS, pH 7.4) solution to 20 ul of collagen dissolved in acidic solution (collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent