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Report error Found 562 of affinity data for UniProtKB/TrEMBL: Q13093
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085629(2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-(1-m...)
Affinity DataKi:  41nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125265(N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2 by mechanistic studiesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117772(N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...)
Affinity DataKi:  0.0300nMAssay Description:Steady state and transient kinetics to a freely reversible, non-covalently bound, human recombinant Phospholipase A2 (rhLp-PLA2) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246902(CHEMBL4076637)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594761(CHEMBL4643118)
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182426(CHEMBL3819543)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant Lp-PLA2 using PED6 as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182427(CHEMBL3181806)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant Lp-PLA2 using PED6 as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant Lp-PLA2 using PED6 as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197675(CHEMBL1369790)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182424(CHEMBL3818090)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant Lp-PLA2 using PED6 as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq | US12378231, Example ABX-1431)
Affinity DataIC50: 4.94E+5nMAssay Description:Inhibition of PLA2G7 in human intact PC3 cells preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363396(CHEMBL1946070)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113313(4,8-Dihydroxy-quinoline-2-carboxylic acid anion | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363380(CHEMBL1945883)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113313(4,8-Dihydroxy-quinoline-2-carboxylic acid anion | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363380(CHEMBL1945883)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363379(CHEMBL1945882)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant N-terminus hexahistidine-tagged human lipoprotein-associated phospholipase A2 expressed in Escherichia coli using 2-thio-PA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363379(CHEMBL1945882)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant N-terminus hexahistidine-tagged human lipoprotein-associated phospholipase A2 expressed in Escherichia coli using 2-thio-PA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429071(CHEMBL2335750)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429070(CHEMBL2335742)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31074(SMR000071147 | cid_130606 | MLS000062611 | N-(6-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429090(Zinquin-E | CHEMBL2335743)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182425(CHEMBL3819345)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant Lp-PLA2 using PED6 as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182425(CHEMBL3819345)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant Lp-PLA2 using 2-thio-PAF as substrate after 20 mins by CPM-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429072(CHEMBL2335752)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085618(5-(6-Methyl-pyridin-3-ylmethyl)-2-(4-phenyl-butyls...)
Affinity DataIC50: 5.50E+4nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197680(CHEMBL3955669)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429073(CHEMBL2335766)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197681(CHEMBL3895499)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161744(3,4-difluorobenzaldehyde O-(3,4-difluorobenzoyl)ox...)
Affinity DataIC50: 3.80E+4nMAssay Description:In vitro inhibitory activity against human lipoprotein-associated phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182430(CHEMBL3819099)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant Lp-PLA2 using 2-thio-PAF as substrate after 20 mins by CPM-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429074(CHEMBL2335754)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161740((E)-(furan-2-ylmethylidene)amino benzoate | CHEMBL...)
Affinity DataIC50: 2.60E+4nMAssay Description:In vitro inhibitory activity against human lipoprotein-associated phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161739((1E,2E)-3-phenylacrylaldehyde O-benzoyloxime | CHE...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory activity against human lipoprotein-associated phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197669(CHEMBL3946955)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085653(2-[7-(4-Chloro-benzenesulfinyl)-heptylsulfanyl]-5-...)
Affinity DataIC50: 1.70E+4nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197659(CHEMBL3975283)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human Lp-PLA2 incubated for 20 mins by Thio-PAF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085642(5-(6-Methyl-pyridin-3-ylmethyl)-2-(5-phenyl-pentyl...)
Affinity DataIC50: 1.40E+4nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429075(CHEMBL2335744)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197679(CHEMBL3908555)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197652(CHEMBL3943407)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Lp-PLA2 in whole human plasma pre-incubated for 15 mins before 2-thio-PAF substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085644(2-[7-(4-Chloro-benzenesulfonyl)-heptylsulfanyl]-5-...)
Affinity DataIC50: 1.26E+4nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085632(5-(6-Methyl-pyridin-3-ylmethyl)-2-(4-phenyl-butoxy...)
Affinity DataIC50: 1.20E+4nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161741((E)-(thiophen-2-ylmethylidene)amino benzoate | CHE...)
Affinity DataIC50: 1.12E+4nMAssay Description:In vitro inhibitory activity against human lipoprotein-associated phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363394(CHEMBL1946068)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240877(Quinolyl derivatives | cyclohexanone O-6-((cyclohe...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant PLA2g7 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50429076(CHEMBL2335756)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197670(CHEMBL3966789)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human Lp-PLA2 pre-incubated for 30 mins before PED6 fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
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