BDBM50107480 CHEMBL348243::N-(4'-Chloro-biphenyl-4-ylmethyl)-2-[2-(4-fluoro-benzylsulfanyl)-4-oxo-5-(2-piperazin-1-yl-pyrimidin-5-ylmethyl)-4H-pyrimidin-1-yl]-N-methyl-acetamide

SMILES CN(Cc1ccc(cc1)-c1ccc(Cl)cc1)C(=O)Cn1cc(Cc2cnc(nc2)N2CCNCC2)c(=O)nc1SCc1ccc(F)cc1

InChI Key InChIKey=WWNRZILQEZDLPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107480   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107480(CHEMBL348243 | N-(4'-Chloro-biphenyl-4-ylmethyl)-2...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed