Affinity DataIC50: 10nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Jak2 in mouse BA/F3 cells expressing TEL-Jak2 assessed as inhibition of STAT5 phosphorylation by Western blotting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of JAK2 in mouse BAF3 cells assessed as reduction in STAT5 phosphorylation incubated for 2 hrs by Western blot methodMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 69nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of JAK2 V617F mutant in BAF3 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 177nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Inhibition of JAK1/JAK2 in mouse whole blood assessed as reduction in IL-6-induced STAT1 phosphorylation in CD8+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataEC50: 186nMAssay Description:Inhibition of JAK2 V617F mutant expressed in mouse BaF3 cells cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
Affinity DataIC50: 234nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 266nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 287nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 302nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 354nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 365nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 372nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 384nMAssay Description:Inhibition of JAK2 in mouse Ba/F3-TEL-JAK2 cells assessed as inhibition of JAK1-driven cell growth incubated for 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 385nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 392nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 431nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 445nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 452nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 593nMAssay Description:Inhibition of JAK2 in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 679nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 695nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
