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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50446982'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446982(CHEMBL3116050)
Affinity DataIC50: <3nMAssay Description:Inhibition of Jak2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446982(CHEMBL3116050)
Affinity DataIC50:  12nMAssay Description:Inhibition of Jak2 in mouse BA/F3 cells expressing TEL-Jak2 assessed as inhibition of STAT5 phosphorylation by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed