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Report error Found 172 of affinity data for UniProtKB/TrEMBL: Q8IU80
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525149(US10988505, Comparative #1)
Affinity DataKi:  0.0110nMAssay Description:Enzymatic assays and Ki determination were performed at room temperature in an assay buffer containing 50 mM Tris-HCl, 150 mM NaCl and 500 μg/mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM236493(US9365853, 4 | US10988505, Comparative #2)
Affinity DataKi:  0.0880nMAssay Description:Enzymatic assays and Ki determination were performed at room temperature in an assay buffer containing 50 mM Tris-HCl, 150 mM NaCl and 500 μg/mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032698(CHEMBL3354676 | N-0130)
Affinity DataKi:  0.130nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525151(US10988505, Example 1)
Affinity DataKi:  0.134nMAssay Description:Enzymatic assays and Ki determination were performed at room temperature in an assay buffer containing 50 mM Tris-HCl, 150 mM NaCl and 500 μg/mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525153(US10988505, Example 3 | N-0386 | Ac-QFR-kbt)
Affinity DataKi:  0.506nMAssay Description:Enzymatic assays and Ki determination were performed at room temperature in an assay buffer containing 50 mM Tris-HCl, 150 mM NaCl and 500 μg/mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525153(US10988505, Example 3 | N-0386 | Ac-QFR-kbt)
Affinity DataKi:  0.510nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  0.600nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032697(CHEMBL3354675)
Affinity DataKi:  0.740nMAssay Description:Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032706(CHEMBL3354683)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236924(CHEMBL4093487)
Affinity DataKi:  1.10nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525256(N-0438 | (H)Arg-Glu-Phe-Arg-kbt)
Affinity DataKi:  1.11nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645308(CHEMBL5562941)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236911(CHEMBL4103740)
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645307(CHEMBL5573803)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645305(CHEMBL5590035)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032698(CHEMBL3354676 | N-0130)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236933(CHEMBL4101897)
Affinity DataKi:  1.5nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645298(CHEMBL5574204)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236914(CHEMBL4091809)
Affinity DataKi:  1.70nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032708(CHEMBL3354685)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236915(CHEMBL4100506)
Affinity DataKi:  2.10nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645296(CHEMBL5575948)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236934(CHEMBL4083908)
Affinity DataKi:  2.30nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032709(CHEMBL3354686)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032707(CHEMBL3354684)
Affinity DataKi:  2.60nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50032707(CHEMBL3354684)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human recombinant matriptase-2 using Boc-Gln-Ala-Arg-AMC as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236931(CHEMBL4104560)
Affinity DataKi:  2.60nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525152(US10988505, Example 2 | N-0385 | Ms-QFR-kbt)
Affinity DataKi:  2.60nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM525152(US10988505, Example 2 | N-0385 | Ms-QFR-kbt)
Affinity DataKi:  2.63nMAssay Description:Enzymatic assays and Ki determination were performed at room temperature in an assay buffer containing 50 mM Tris-HCl, 150 mM NaCl and 500 μg/mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236929(CHEMBL4103673)
Affinity DataKi:  3.10nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236938(CHEMBL4086405)
Affinity DataKi:  3.10nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50420334(CHEMBL2086421)
Affinity DataKi:  3.30nMAssay Description:Tight binding inhibition of human matriptase2 expressed in Drosophila melanogaster S2 cells using Boc-QAR-AMC as substrate incubated for 15 mins prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236919(CHEMBL4073691)
Affinity DataKi:  3.5nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645301(CHEMBL5571372)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645302(CHEMBL5569773)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236926(CHEMBL4101235)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human TMPRSS6 transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645297(CHEMBL5592173)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236937(CHEMBL4074504)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236917(CHEMBL4099552)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236922(CHEMBL4089262)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  5.20nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236925(CHEMBL4084785)
Affinity DataKi:  5.20nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236927(CHEMBL4065870)
Affinity DataKi:  5.30nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  5.30nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50236936(CHEMBL4073533)
Affinity DataKi:  5.30nMAssay Description:Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
SociÉTÉ

US Patent
LigandPNGBDBM50031706(4-Guanidino-benzoic acid 4-dimethylcarbamoylmethox...)
Affinity DataKi:  5.60nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
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