Compile Data Set for Download or QSAR
Report error Found 1762 of affinity data for UniProtKB/TrEMBL: Q8TDV5
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342703BDBM50342703(rac-4-(3-(2-(3-(1-(5-chloropyrimidin-2-yl)piperidi...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232631BDBM50232631(CHEMBL4104464)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342697BDBM50342697((+)-trans-4-(2-(2-(1-(5-chloropyrimidin-2-yl)piper...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342697BDBM50342697((+)-trans-4-(2-(2-(1-(5-chloropyrimidin-2-yl)piper...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232627BDBM50232627(CHEMBL4098051)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50036640BDBM50036640(CHEMBL3354778)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human GPR119 overexpressed in CHO cells assessed as increase in cellular cAMP production by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50343443BDBM50343443(tert-butyl 4-(1-(2-fluoro-4-(methylsulfonyl)phenyl...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50343444BDBM50343444(tert-butyl 4-(9-(2-fluoro-4-(methylsulfonyl)phenyl...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50204219BDBM50204219(CHEMBL3893596)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244791BDBM50244791((2-Fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopr...)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244791BDBM50244791((2-Fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopr...)
Affinity DataEC50:  0.680nMAssay Description:Agonist activity at CPR119 transfected in Xenopus dermal melanophore assessed as dispersion of melatonin-induced pigmentationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232629BDBM50232629(CHEMBL4077033)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50343445BDBM50343445(tert-butyl 4-(3-(4-(methylsulfonyl)phenyl)isoxazol...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50122947BDBM50122947(CHEMBL3622182)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232622BDBM50232622(CHEMBL4060838)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232625BDBM50232625(CHEMBL4080222)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50343446BDBM50343446(tert-butyl 4-(1-(2-fluoro-4-(methylsulfonyl)phenyl...)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50013912BDBM50013912(CHEMBL3260536)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50420842BDBM50420842(CHEMBL2086684)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]-N-(2-fluoro-4-methylsulfonyl-phenyl)-6-[4-(3-isopropyl-1,2,4-oxadiazol-5-yl)-1-piperidyl]-5-nitro-pyrimidin-4-amine from human G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433856BDBM50433856(CHEMBL2382410)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]-N-(2-fluoro-4-methylsulfonyl-phenyl)-6-[4-(3-isopropyl-1,2,4-oxadiazol-5-yl)-1-piperidyl]-5-nitro-pyrimidin-4-amine from human G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342680BDBM50342680(tert-butyl 1'-(2-cyano-6-methylpyrimidin-4-yl)-4,4...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50036636BDBM50036636(CHEMBL3354774)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human GPR119 overexpressed in CHO cells assessed as increase in cellular cAMP production by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50122756BDBM50122756(CHEMBL3622179)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50343447BDBM50343447(tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyra...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50240387BDBM50240387(CHEMBL4098760)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in cAMP stimulation measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50106208BDBM50106208(CHEMBL3598101)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50204225BDBM50204225(CHEMBL3912040)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50204229BDBM50204229(CHEMBL3982536)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427059BDBM50427059(CHEMBL2322837)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human GPR119 transfected in HEK293 cells assessed as concentration for 50 % cAMP stimulation of oleylethanolamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244681BDBM50244681({6-[4-(3-tert-Butyl-[1,2,4]oxadiazol-5-yl)-piperid...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at CPR119 transfected in Xenopus dermal melanophore assessed as dispersion of melatonin-induced pigmentationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50204226BDBM50204226(CHEMBL3914281)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50122933BDBM50122933(CHEMBL3622166)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427063BDBM50427063(CHEMBL2322841)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 transfected in HEK293 cells assessed as concentration for 50 % cAMP stimulation of oleylethanolamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232626BDBM50232626(CHEMBL4070965)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50204231BDBM50204231(CHEMBL3951013)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427059BDBM50427059(CHEMBL2322837)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 transfected in HEK293 cells assessed as concentration for 50 % cAMP stimulation of oleylethanolamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50204223BDBM50204223(CHEMBL3904015)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50122936BDBM50122936(CHEMBL3622181)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50122870BDBM50122870(CHEMBL3622171)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50540315BDBM50540315(CHEMBL4639701)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells preincubated for 30 mins followed by d2 cAMP addition and measured after 60 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50122931BDBM50122931(CHEMBL3622168)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232632BDBM50232632(CHEMBL4083676)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50240388BDBM50240388(CHEMBL4078300)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in cAMP stimulation measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342701BDBM50342701(2-(4-((1R,2S)-2-(2-(5-(1H-1,2,3-triazol-1-yl)pyrid...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342702BDBM50342702(6-methyl-2-(2-((1S,2R)-2-(1-(5-methylpyrimidin-2-y...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50342681BDBM50342681(tert-butyl 1'-(6-cyano-2-methylpyrimidin-4-yl)-4,4...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50268856BDBM50268856(CHEMBL4079458)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50036671BDBM50036671(CHEMBL3354804)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 overexpressed in CHO cells assessed as increase in cellular cAMP production by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232628BDBM50232628(CHEMBL4097638)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
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