Found 7 Enz. Inhib. hit(s) with Target = 'Glucose-dependent insulinotropic receptor' and Ligand = 'BDBM50244791' TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at human GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 0.680nMAssay Description:Agonist activity at CPR119 (unknown origin) transfected in Xenopus dermal melanophore assessed as dispersion of melatonin-induced pigmentationMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 0.650nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 640nMAssay Description:Agonist activity at CREB-LBD and Gal4-DBD fused recombinant human GPR119 expressed in HEK293 cells by firefly luciferase assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 4.80nMAssay Description:Agonist activity at recombinant human GPR119 expressed in HEK293 cells after 24 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Agonist activity at human GPR119 stably transfected in CHO-K1 cells assessed as increase in cAMP stimulation after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Agonist activity at CREB-LBD and GAL4-DBD fused human GPR119 expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
