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Report error Found 2450 for UniProtKB: Q92847
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365814(CHEMBL1956993)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365815(CHEMBL1956994)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50292221((S)-3-(2,4-Dichloro-phenyl)-1-(2-diethylamino-ethy...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365831(CHEMBL1957010)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50412965(CHEMBL480821)
Affinity DataEC50:  0.0501nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50047485(CHEMBL3319217)
Affinity DataIC50: 0.0780nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50267262(CHEMBL501253)
Affinity DataIC50: 0.0800nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50280856(CHEMBL4172656)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50280856(CHEMBL4172656)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365822(CHEMBL1957001)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50267261(CHEMBL525994)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50422313(CHEMBL2310891)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50366689(GHRELIN)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50049478(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)
Affinity DataKd:  0.140nMAssay Description:Compound was evaluated for binding affinity using [35S]MK-0677 (800-1100 Ci/mmol), as radioligand having specific high activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544367(CHEMBL4641513)
Affinity DataEC50:  0.145nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50047481(CHEMBL3319221)
Affinity DataIC50: 0.150nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50412966(CHEMBL481013)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50412954(SB-791016 | SB-791016A | CHEMBL251572)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544361(CHEMBL4635542)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50412954(SB-791016 | SB-791016A | CHEMBL251572)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at GSHR by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544367(CHEMBL4641513)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50422316(CHEMBL2310888)
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365809(CHEMBL1956990)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50626067(CHEMBL5403042)
Affinity DataIC50: 0.160nMAssay Description:Displacement of [35S]MK-0677 from human GHSR1a expressed in HEK293 cell membrane by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544361(CHEMBL4635542)
Affinity DataEC50:  0.168nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50477764(CHEMBL401134)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at GSHR by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544368(CHEMBL4638297)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365812(CHEMBL1956991)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50412978(CHEMBL518774)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50376781(CHEMBL410085)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50379328(CHEMBL2011825)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human GHSR1a receptor assessed as intracellular Ca2+ concentration by aequorin luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50376783(CHEMBL259166)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365820(CHEMBL1956999)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50376760(CHEMBL410074)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM19386(6-[(benzyloxy)methyl]-5-(4-{[(4-nitrophenyl)methyl...)
Affinity DataIC50: 0.200nM EC50:  5.80nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50066086(1N-{6-[1'-[2-(1-amino-1-methylethylcarboxamido)-3-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration (biotinylated probe) is evaluated for [35S]- MK-0677 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544368(CHEMBL4638297)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50094223(CHEMBL3586033)
Affinity DataIC50: 0.230nMAssay Description:Binding affinity to ghrelin receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544379(CHEMBL4643530)
Affinity DataEC50:  0.235nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50047429(CHEMBL3319398)
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50049478(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)
Affinity DataKi:  0.240nMAssay Description:Binding Affinity against Growth hormone secretagogue receptor of swine using [35S]MK-0677 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50292225((S)-3-(2,5-Dichloro-phenyl)-1-(2-diethylamino-ethy...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50366689(GHRELIN)
Affinity DataIC50: 0.25nMAssay Description:Binding affinity towards human Growth hormone secretagogue receptor type 1 using competitive binding assay with radiolabeled [35S]-MK-0677 expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50626066(CHEMBL5410324)
Affinity DataIC50: 0.25nMAssay Description:Displacement of [35S]MK-0677 from human GHSR1a expressed in HEK293 cell membrane by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM21940(Ghrelin | US20240190875, Example Ghrelin)
Affinity DataIC50: 0.25nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50412963(CHEMBL481796)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544363(CHEMBL4640507)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50544379(CHEMBL4643530)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365828(CHEMBL1957007)
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM50365830(CHEMBL1957009)
Affinity DataKi:  0.270nMAssay Description:Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
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