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Found 6 Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM19331'
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50:  0.300nM EC50:  3nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Cnrs

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed