Compile Data Set for Download or QSAR
Report error Found 35 of affinity data for UniProtKB/TrEMBL: Q99KQ4
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438936BDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81395BDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236217BDBM50236217(CHEMBL4061448)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515548BDBM50515548(CHEMBL4458472)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236220BDBM50236220(CHEMBL4074848)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81395BDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236219BDBM50236219(CHEMBL4066091)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515544BDBM50515544(CHEMBL4535593)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236221BDBM50236221(CHEMBL4078882)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515540BDBM50515540(CHEMBL4470375)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515543BDBM50515543(CHEMBL4464821)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438936BDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236223BDBM50236223(CHEMBL4083606)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515551BDBM50515551(CHEMBL4446772)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515552BDBM50515552(CHEMBL4469394)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515556BDBM50515556(CHEMBL4555764)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236222BDBM50236222(CHEMBL4101611)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236224BDBM50236224(CHEMBL4088492)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515541BDBM50515541(CHEMBL4590810)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515546BDBM50515546(CHEMBL4577703)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515545BDBM50515545(CHEMBL4440197)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515547BDBM50515547(CHEMBL4444551)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236216BDBM50236216(CHEMBL4064240)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515542BDBM50515542(CHEMBL4569066)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236218BDBM50236218(CHEMBL4094769)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011266BDBM50011266(CHEMBL3260358)
Affinity DataIC50: 59nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011266BDBM50011266(CHEMBL3260358)
Affinity DataEC50:  70nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515553BDBM50515553(CHEMBL4567518)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515550BDBM50515550(CHEMBL4462010)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236215BDBM50236215(CHEMBL4087071)
Affinity DataIC50: 269nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515555BDBM50515555(CHEMBL4070645)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515554BDBM50515554(CHEMBL4561248)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515549BDBM50515549(CHEMBL4555772)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644548BDBM50644548(CHEMBL5571277)
Affinity DataEC50:  1.49E+3nMAssay Description:Activation of N-terminal 6His-tagged mouse NAMPT measured for 20 mins by fluorescence based spectrometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644014BDBM50644014(CHEMBL5572201)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of N-terminal His-tagged mouse NAMPT transformed in Escherichia coli Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed