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TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444582BDBM50444582(CHEMBL3099715)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444582BDBM50444582(CHEMBL3099715)
Affinity DataKd:  25nMAssay Description:Binding affinity to C-terminal 6xHis-tagged Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131483BDBM50131483(CHEMBL3632788)
Affinity DataIC50: 36nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131487BDBM50131487(CHEMBL3634881)
Affinity DataIC50: 40nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131401BDBM50131401(CHEMBL3632791)
Affinity DataIC50: 42nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131438BDBM50131438(CHEMBL3632777)
Affinity DataIC50: 57nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131421BDBM50131421(CHEMBL3632770)
Affinity DataIC50: 59nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131484BDBM50131484(CHEMBL3632789)
Affinity DataIC50: 68nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131486BDBM50131486(CHEMBL3634880)
Affinity DataIC50: 77nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131412BDBM50131412(CHEMBL3632794)
Affinity DataIC50: 84nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131485BDBM50131485(CHEMBL3632790)
Affinity DataIC50: 100nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131407BDBM50131407(CHEMBL3632793)
Affinity DataIC50: 110nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131424BDBM50131424(CHEMBL3632772)
Affinity DataIC50: 110nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131430BDBM50131430(CHEMBL3632775)
Affinity DataIC50: 120nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131439BDBM50131439(CHEMBL3632778)
Affinity DataIC50: 160nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131413BDBM50131413(CHEMBL3632795)
Affinity DataIC50: 170nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444581BDBM50444581(CHEMBL3099713)
Affinity DataIC50: 220nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131419BDBM50131419(CHEMBL3632769)
Affinity DataIC50: 220nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131422BDBM50131422(CHEMBL3632771)
Affinity DataIC50: 220nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444580BDBM50444580(CHEMBL3099714)
Affinity DataIC50: 230nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131425BDBM50131425(CHEMBL3632773)
Affinity DataIC50: 260nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131405BDBM50131405(CHEMBL3632792)
Affinity DataIC50: 270nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131426BDBM50131426(CHEMBL3632774)
Affinity DataIC50: 350nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131455BDBM50131455(CHEMBL3632783)
Affinity DataIC50: 400nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131491BDBM50131491(CHEMBL3634885)
Affinity DataIC50: 410nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131454BDBM50131454(CHEMBL3632782)
Affinity DataIC50: 430nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444676BDBM50444676(CHEMBL1807815)
Affinity DataIC50: 430nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131447BDBM50131447(CHEMBL3632780)
Affinity DataIC50: 470nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131494BDBM50131494(CHEMBL3634888)
Affinity DataIC50: 470nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131488BDBM50131488(CHEMBL3634882)
Affinity DataIC50: 500nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131477BDBM50131477(CHEMBL3632785)
Affinity DataIC50: 530nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131482BDBM50131482(CHEMBL3632787)
Affinity DataIC50: 550nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131492BDBM50131492(CHEMBL3634886)
Affinity DataIC50: 670nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131493BDBM50131493(CHEMBL3634887)
Affinity DataIC50: 690nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131443BDBM50131443(CHEMBL3632779)
Affinity DataIC50: 740nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131495BDBM50131495(CHEMBL3632764)
Affinity DataIC50: 810nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131417BDBM50131417(CHEMBL3632767)
Affinity DataIC50: 970nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131448BDBM50131448(CHEMBL3632781)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131416BDBM50131416(CHEMBL3632766)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131457BDBM50131457(CHEMBL3632784)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131490BDBM50131490(CHEMBL3634884)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131437BDBM50131437(CHEMBL3632776)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395801BDBM50395801(CHEMBL2165173)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395800BDBM50395800(CHEMBL2165174)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131415BDBM50131415(CHEMBL3632765)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444677BDBM50444677(CHEMBL3098806)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444687BDBM50444687(CHEMBL3098811)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Staphylococcus aureus LigAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444578BDBM50444578(CHEMBL3099706)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to C-terminal 6xHis-tagged Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131418BDBM50131418(CHEMBL3632768)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131489BDBM50131489(CHEMBL3634883)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Staphylococcus aureus NAD(+)-dependent DNA ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
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