44 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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4
Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase III (PI4KB).
Academy of Sciences of The Czech Republic
35
Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase III (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology.
Academy of Sciences of The Czech Republic
4
Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.
Academy of Sciences of The Czech Republic
10
Neurosteroid-like Inhibitors of N-Methyl-d-aspartate Receptor: Substituted 2-Sulfates and 2-Hemisuccinates of Perhydrophenanthrene.
Academy of Sciences of The Czech Republic
6
Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases.
Academy of Sciences of The Czech Republic
11
Design of highly potent urea-based, exosite-binding inhibitors selective for glutamate carboxypeptidase II.
Academy of Sciences of The Czech Republic
20
Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery.
Academy of Sciences of The Czech Republic
10
Malonate-based inhibitors of mammalian serine racemase: kinetic characterization and structure-based computational study.
Academy of Sciences of The Czech Republic
1
Norbornane-based nucleoside and nucleotide analogues locked in North conformation.
Academy of Sciences of The Czech Republic
36
Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides.
Academy of Sciences of The Czech Republic
5
The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
Academy of Sciences of The Czech Republic
4
The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.
Academy of Sciences of The Czech Republic
1
Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles.
Academy of Sciences of The Czech Republic
1
Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2.
Academy of Sciences of The Czech Republic
23
Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, Plasmodium falciparum and Plasmodium vivax 6-oxopurine phosphoribosyltransferases.
Academy of Sciences of The Czech Republic
22
Activation of human RNase L by 2'- and 5'-O-methylphosphonate-modified oligoadenylates.
Academy of Sciences of The Czech Republic
2
N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.
Academy of Sciences of The Czech Republic
17
Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
Academy of Sciences of The Czech Republic
2
A phenylnorstatine inhibitor binding to HIV-1 protease: geometry, protonation, and subsite-pocket interactions analyzed at atomic resolution.
Academy of Sciences of The Czech Republic
15
2,6,8,9-tetrasubstituted purines as new CDK1 inhibitors.
Academy of Sciences of The Czech Republic
2
Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.
Academy of Sciences of The Czech Republic
10
Novel substrate-based inhibitors of human glutamate carboxypeptidase II with enhanced lipophilicity.
Academy of Sciences of The Czech Republic
19
Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
Academy of Sciences of The Czech Republic
16
Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines.
Academy of Sciences of The Czech Republic
4
Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides.
Academy of Sciences of The Czech Republic
3
8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase.
Academy of Sciences of The Czech Republic
2
Synthesis and evaluation of 17alpha-arylestradiols as ligands for estrogen receptor alpha and beta.
Academy of Sciences of The Czech Republic
4
Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Academy of Sciences of The Czech Republic
8
Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase.
Academy of Sciences of The Czech Republic
4
HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site.
Academy of Sciences of The Czech Republic
6
S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase.
Academy of Sciences of The Czech Republic
6
Activation of murine RNase L by isopolar 2'-phosphonate analogues of 2',5' oligoadenylates.
Academy of Sciences of The Czech Republic
23
Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors.
Academy of Sciences of The Czech Republic
35
Synthesis and evaluation of 2-pyridinylpyrimidines as inhibitors of HIV-1 structural protein assembly.
Academy of Sciences of The Czech Republic
9
Structure-aided design of novel inhibitors of HIV protease based on a benzodiazepine scaffold.
Academy of Sciences of The Czech Republic
7
Inorganic polyhedral metallacarborane inhibitors of HIV protease: a new approach to overcoming antiviral resistance.
Academy of Sciences of The Czech Republic
54
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.
Academy of Sciences of The Czech Republic
7
Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain.
Academy of Sciences of The Czech Republic
10
RUTHENIUM COMPLEXES FOR INHIBITION OF GALECTINS, METHOD OF THEIR PREPARATION, AND USE THEREOF
Academy of Sciences of the Czech Republic
7
Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine.
Academy of Sciences of The Czech Republic
1
Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro.
Academy of Sciences of The Czech Republic
7
Modulation of aldose reductase inhibition by halogen bond tuning.
Academy of Sciences of The Czech Republic
24
Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
Academy of Sciences of The Czech Republic