Binding Database

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Recent Progress in Histone Demethylase Inhibitors.

University of Oxford

Inhibition of Histone Demethylases Offers a Novel and Promising Approach for the Treatment of Cancer and Other Diseases.

Therachem Research Medilab (India)

Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).

Hangzhou Normal University

Small-Molecule Inhibitors of the MLL1 CXXC Domain, an Epigenetic Reader of DNA Methylation.

University of Virginia

Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.

Genentech

Identification of potent, selective KDM5 inhibitors.

Constellation Pharmaceuticals

Structure-based design and discovery of potent and selective KDM5 inhibitors.

Celgene

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

Celgene Quanticel Research

From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.

Genentech

Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors.

Sichuan University

[3H]cytisine binding to nicotinic cholinergic receptors in brain.

Georgetown University

The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family.

Cnrs

Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.

University of Padova