Binding Database

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.

Glaxosmithkline

Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.

University of Oxford

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.

Glaxosmithkline

Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors.

University of Oxford

Recent Advances with KDM4 Inhibitors and Potential Applications.

St. Jude Children'S Research Hospital

Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).

Hangzhou Normal University

First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.

University of Oxford

Discovery of a new class of JMJD6 inhibitors and structure-activity relationship study.

Nankai University

Discovery of a potent and selective inhibitor of histone lysine demethylase KDM4D.

Nankai University

Structure-based design and discovery of potent and selective KDM5 inhibitors.

Celgene

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

Celgene Quanticel Research

Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors.

Sichuan University