PMID

Data

Article Title

Organization

Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.

Harvard Medical School

Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase.

Harvard Medical School

The lipogenesis pathway as a cancer target.

Wayne State University

The biology and chemistry of hyperlipidemia.

Sinhgad College of Pharmacy

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.

Bristol-Myers Squibb Pharmaceutical Research Institute

ATP-Citrate lyase as a target for hypolipidemic intervention. 2. Synthesis and evaluation of (3R,5S)-omega-substituted-3-carboxy-3, 5-dihydroxyalkanoic acids and their gamma-lactone prodrugs as inhibitors of the enzyme in vitro and in vivo.

Smithkline Beecham Pharmaceuticals

ATP-citrate lyase as a target for hypolipidemic intervention. Design and synthesis of 2-substituted butanedioic acids as novel, potent inhibitors of the enzyme.

Smithkline Beecham Pharmaceuticals

ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism.

University of Pisa