PMID

Data

Article Title

Organization

Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues.

University of Montpellier

The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2.

Rti International

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.

Research Triangle Institute

Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2.

Research Triangle Institute

Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.

Research Triangle Institute

The synthesis of neurotensin antagonist SR 48692 for prostate cancer research.

Durham University

Ketomethylene and (cyanomethylene)amino pseudopeptide analogues of the C-terminal hexapeptide of neurotensin.

Instituto De Qu£Mica M£Dica (Csic)

 

Preparation of neurotensin analogs with a novel pro-tyr replacement

TBA

 

Neurotensin receptor binding and antinociceptive activity for lipophilic N-amido neurotensin(913) analogs

TBA

Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.

Medical University of South Carolina Campus

 

Synthesis of partially non-peptidic neurotensin mimetics

TBA

 

Stable isosteres of neurotensin c-terminal pentapeptides derived by modification of the amide function

TBA

 

UK-73,093: A non-peptide neurotensin receptor antagonist

TBA

Hormone-like conopeptides - new tools for pharmaceutical design.

University of Queensland

Discovery of ?-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.

Sanford Burnham Prebys Medical Discovery Institute