Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50045007
TargetNeurotensin receptor type 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataKi:  2nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataKi:  7nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataEC50: >10nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041429(CHEMBL3356854)
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKi:  21nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041429(CHEMBL3356854)
Affinity DataKi: >25nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041427(CHEMBL3356853)
Affinity DataKi: >25nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataKi: >25nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as inhibition of SR142948a-induced calcium release by FLIPR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041429(CHEMBL3356854)
Affinity DataKi:  88nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041427(CHEMBL3356853)
Affinity DataEC50:  145nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataKi:  474nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041427(CHEMBL3356853)
Affinity DataKi:  959nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataIC50: 1.07E+3nMAssay Description:Antagonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as inhibition of SR142948a-induced calcium release by FLIPR ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed