BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.2M Compounds and 9.3K Targets. Of those, 1,352K data for 627K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Carbamazepine derivatives with P2X4 receptor-blocking activity.EBI
University of Bonn
Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist.EBI
Roche Palo Alto
N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.EBI
University of Bonn
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.EBI
Abbott Laboratories
Purine and pyrimidine (P2) receptors as drug targets.EBI
National Institute of Diabetes
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.EBI
Roche Palo Alto
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.EBI
Roche Palo Alto
Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist.EBI
Roche Palo Alto
Recent advancements in mechanistic studies and structure activity relationship of FEBI
Kurukshetra University