PMID

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Article Title

Organization

Synthesis and binding profile of haloperidol-based bivalent ligands targeting dopamine D(2)-like receptors.

Friedrich-Alexander University

Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers.

Friedrich-Alexander University

Functionally selective dopamine D2/D3 receptor agonists comprising an enyne moiety.

Friedrich-Alexander University

Novel azulene derivatives for the treatment of erectile dysfunction.

Friedrich-Alexander University

Discovery of a dopamine D4 selective PET ligand candidate taking advantage of a click chemistry based REM linker.

Clinic of Nuclear Medicine

Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET.

Friedrich-Alexander University

trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist.

Purdue University

2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist.

Laboratoire De Chimie Th�Rapeutique

Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists.

Friedrich-Alexander University

Fancy bioisosteres: metallocene-derived G-protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles.

Friedrich-Alexander University

Bivalent molecular probes for dopamine D2-like receptors.

Friedrich-Alexander University

Evaluation of 18F-labeled benzodioxine piperazine-based dopamine D4 receptor ligands: lipophilicity as a determinate of nonspecific binding.

Forschungszentrum J£Lich

Development of a bivalent dopamine D2 receptor agonist.

Friedrich-Alexander University

Bivalent dopamine D2 receptor ligands: synthesis and binding properties.

Friedrich-Alexander University

Aromatic ring functionalization of benzolactam derivatives: new potent dopamine D3 receptor ligands.

University of Santiago De Compostela

Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions.

Friedrich-Alexander University

Synthesis, biological evaluation and radiolabelling by 18F-fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET.

Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Novel pyridylmethylamines as highly selective 5-HT(1A) superagonists.

Friedrich-Alexander University

Bioisosteric replacement leading to biologically active [2.2]paracyclophanes with altered binding profiles for aminergic G-protein-coupled receptors.

Friedrich-Alexander University

1,1'-Disubstituted ferrocenes as molecular hinges in mono- and bivalent dopamine receptor ligands.

Friedrich-Alexander University

Parallel synthesis of potent dopaminergic N-phenyltriazole carboxamides applying a novel click chemistry based phenol linker.

Friedrich-Alexander University

Novel D3 selective dopaminergics incorporating enyne units as nonaromatic catechol bioisosteres: synthesis, bioactivity, and mutagenesis studies.

Friedrich-Alexander University

Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes.

Friedrich-Alexander University

In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors.

Johannes Gutenberg University

Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands.

Friedrich-Alexander University

Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype.

Friedrich-Alexander University

Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents.

University of Erlangen-Nuremberg

Research progress in biological activities of isochroman derivatives.

Shaanxi University of Chinese Medicine

Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.

University of Erlangen-Nuremberg