BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO).EBI
Zhengzhou University
Structural basis for inhibition of the fat mass and obesity associated protein (FTO).EBI
University of Oxford
Small molecules that regulate the N6-methyladenosine RNA modification as potential anti-cancer agents.EBI
University of Connecticut
Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity.EBI
Sichuan University
Discovery of Pyrazolo[1,5-EBI
China Pharmaceutical University
Novel 1,8-Naphthalimide Derivatives As Antitumor Agents and Potent Demethylase Inhibitors.EBI
Nanjing Normal University
Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties.EBI
University of Chinese Academy of Sciences
Recent developments of small molecules targeting RNA mEBI
China Pharmaceutical University
Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.EBI
University College London
Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors.EBI
University of Oxford
Rational Design and Optimization of mEBI
University of California San Diego
Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach.EBI
Kyoto Prefectural University of Medicine
Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors.EBI
Chinese Academy of Sciences
Discovery of a potent, selective and cell active inhibitor of mEBI
Nankai University
1-(5-(2-CYANOPYRIDIN-4-YL)OXAZOLE-2-CARBONYL)-4-METHYLHEXAHYDROPYRROLO[3,4-B]PYR ROLE-5(1H)-CARBONITRILE AS USP30 INHIBITOR FOR USE IN THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION, CANCER AND FIBROSISBDB
Mission Therapeutics