Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50016081
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592094BDBM50592094(CHEMBL5203605)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592105BDBM50592105(CHEMBL5172537)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592118BDBM50592118(CHEMBL5205465)
Affinity DataIC50: 396nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592104BDBM50592104(CHEMBL5175898)
Affinity DataIC50: 421nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592117BDBM50592117(CHEMBL5186162)
Affinity DataIC50: 559nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592096BDBM50592096(CHEMBL5208142)
Affinity DataIC50: 591nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592100BDBM50592100(CHEMBL5180828)
Affinity DataIC50: 727nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592116BDBM50592116(CHEMBL5202184)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human full length N-terminal His6-tagged ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592109BDBM50592109(CHEMBL5195733)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592072BDBM50592072(CHEMBL5186888)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592101BDBM50592101(CHEMBL5207507)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592122BDBM50592122(CHEMBL5169831)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH3 (1 to 286 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592120BDBM50592120(CHEMBL5201520)
Affinity DataIC50: 6.61E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592099BDBM50592099(CHEMBL5194233)
Affinity DataIC50: 6.62E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged FTO (1 to 505 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592121BDBM50592121(CHEMBL5178457)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592114BDBM50592114(CHEMBL5178434)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592107BDBM50592107(CHEMBL5205133)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592077BDBM50592077(CHEMBL5208141)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592076BDBM50592076(CHEMBL5179539)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592079BDBM50592079(CHEMBL5169548)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592078BDBM50592078(CHEMBL5205753)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592081BDBM50592081(CHEMBL5190440)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592080BDBM50592080(CHEMBL5180799)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592083BDBM50592083(CHEMBL5191814)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592082BDBM50592082(CHEMBL5187025)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592085BDBM50592085(CHEMBL5197389)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592084BDBM50592084(CHEMBL5174267)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592087BDBM50592087(CHEMBL5196291)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592086BDBM50592086(CHEMBL5178156)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592089BDBM50592089(CHEMBL5199644)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592088BDBM50592088(CHEMBL5195082)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592091BDBM50592091(CHEMBL5180139)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592090BDBM50592090(CHEMBL5177633)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592094BDBM50592094(CHEMBL5203605)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of FTO (unknown origin) mediated demethylation of m6A assessed as disruption of enzyme substrate binding by fluorescence polarisation assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592073BDBM50592073(CHEMBL5169366)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592075BDBM50592075(CHEMBL5181590)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592074BDBM50592074(CHEMBL5201436)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592108BDBM50592108(CHEMBL5205949)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592111BDBM50592111(CHEMBL5209212)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592110BDBM50592110(CHEMBL5192668)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592113BDBM50592113(CHEMBL5206378)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592112BDBM50592112(CHEMBL5177920)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592115BDBM50592115(CHEMBL5188997)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592119BDBM50592119(CHEMBL5203551)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNucleic acid dioxygenase ALKBH1(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592094BDBM50592094(CHEMBL5203605)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ALKHB1 (unknown origin) mediated demethylation of m6A assessed as enzyme substrate binding by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592093BDBM50592093(CHEMBL5171235)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
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