19 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
The recent advance of Interleukin-1 receptor associated kinase 4 inhibitors for the treatment of inflammation and related diseases.
Children's Hospital Affiliated to Zhengzhou University
Novel Azepino[4,5-b]indolone as cGAS Inhibitors for Treating Immune-Mediated Diseases.
Smith, Gambrell & Russell
Inhibitors of the Cyclic GMP-AMP Synthase (cGAS) as Potential Treatment for Autoimmune and Inflammatory Diseases.
PI Health Sciences
Design, Synthesis, and Pharmacological Evaluation of Spiro[carbazole-3,3'-pyrrolidine] Derivatives as cGAS Inhibitors for Treatment of Acute Lung Injury.
Shanghai Jiao Tong University
Small molecules targeting cGAS-STING pathway for autoimmune disease.
Shanghai Jiao Tong University
Small molecule approaches to treat autoimmune and inflammatory diseases (Part II): Nucleic acid sensing antagonists and inhibitors.
Roche Innovation Center Shanghai
Synthesis and Pharmacological Evaluation of Tetrahydro-γ-carboline Derivatives as Potent Anti-inflammatory Agents Targeting Cyclic GMP-AMP Synthase.
Shanghai Institute of Materia Medica (Simm)
Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
Pfizer
COMPOUND SERVING AS MASP-2 INHIBITOR, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF
Wuhan Createrna Science And Technology Co.
N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV 1.7 AND/OR NAV 1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME AND KITS
Eurofarma
Pyridine derivatives with c-linked cyclic substituents as cGAS inhibitors
Boehringer Ingelheim International
Substituted amino six-membered nitric heterocyclic ring compound and preparation and use thereof
Shanghai Institute of Materia Medica