Report error Found 83 Enz. Inhib. hit(s) with all data for entry = 50021734
Affinity DataIC50: 6nMAssay Description:Inhibition of full length recombinant human cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo max luminescent kinase as...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of full length human cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of full length recombinant human cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo max luminescent kinase as...More data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Binding affinity to human cGAS assessed as dissociation constant measured upto 240 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of full length recombinant human cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo max luminescent kinase as...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human cGas incubated for 120 minsMore data for this Ligand-Target Pair
Affinity DataKd: 146nMAssay Description:Binding affinity to human cGAS assessed as dissociation constant measured upto 240 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human cGas assessed as dissociation constantMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 442nMAssay Description:Inhibition of full length mouse cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of mouse cGasMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of cGAS in dsDNA activated mouse RAW-Lucia ISG cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by lumines...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of cGAS in dsDNA stimulated human THP-1 cells assessed as inhibition of IFNB1 mRNA level by qRT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of cGAS in dsDNA stimulated human THP-1 cells assessed as inhibition of IFNB1 mRNA level by qRT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of mouse cGas incubated for 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of cGAS in dsDNA stimulated human THP-1 cells assessed as inhibition of IFNB1 mRNA level by qRT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of cGAS in dsDNA activated mouse RAW-Lucia ISG cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by lumines...More data for this Ligand-Target Pair
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 4.26E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of cGAS in dsDNA activated mouse RAW-Lucia ISG cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by lumines...More data for this Ligand-Target Pair
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of cGAS in mouse RAW-Lucia ISG cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUAN...More data for this Ligand-Target Pair
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human full length cGas (1 to 522 residues) expressed in Escherichia coli Rosetta (DE3) incubated for 90 mins by pyrophosphatase-coupled...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human cGas in presence of ATP by mass spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of full length mouse cGAS expressed in Escherichia coli BL21 (DE3) incubated for 7 hrs by Kinase-glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.22E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 5.86E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 6.41E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 6.45E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 6.45E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 6.94E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 7.15E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of cGAS in dsDNA activated human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescenc...More data for this Ligand-Target Pair
