BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
32
Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.EBI
Abbvie Deutschland
23
Novel, potent, selective, and brain penetrant phosphodiesterase 10A inhibitors.EBI
Abbvie Deutschland
26
Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists.EBI
Abbvie Deutschland
26
Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.EBI
Abbvie Deutschland
33
Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.EBI
Abbvie Deutschland
34
Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides.EBI
Abbvie Deutschland
124
Inhibitor compounds of phosphodiesterase type 10ABDB
Abbvie Deutschland
88
Substituted pyrazolopyrimidines and method of useBDB
Abbvie Deutschland
44
Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseasesBDB
Abbvie Deutschland
35
Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland
17
Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland
7
Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitorsBDB
Abbvie Deutschland
76
Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland
302
Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland
10
Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland
3
Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland
36
Oxindole compounds carrying a nitrogen-bound spiro substituent and use thereof for treating vasopressin-related diseasesBDB
Abbvie Deutschland