BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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35 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
4
Selenophene-containing inhibitors of type IIA bacterial topoisomerases.EBI
Achillion Pharmaceuticals
4
In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates.EBI
Achillion Pharmaceuticals
6
Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.EBI
Achillion Pharmaceuticals
17
Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells.EBI
Achillion Pharmaceuticals
40
Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus.EBI
Achillion Pharmaceuticals
7
Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).EBI
Achillion Pharmaceuticals
5
Dual targeting of DNA gyrase and topoisomerase IV: target interactions of heteroaryl isothiazolones in Staphylococcus aureus.EBI
Achillion Pharmaceuticals
7
Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions.EBI
Achillion Pharmaceuticals
76
HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERSBDB
Achillion Pharmaceuticals
54
Macrocyclic compounds for the treatment of medical disordersBDB
Achillion Pharmaceuticals
563
Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
8
Amide compounds for treatment of immune and inflammatory disordersBDB
Achillion Pharmaceuticals
118
Pharmaceutical compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
121
Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disordersBDB
Achillion Pharmaceuticals
34
Quinazoline and indole compounds to treat medical disordersBDB
Achillion Pharmaceuticals
223
Macrocyclic compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
565
Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
13
Disubstituted compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
34
Quinazoline and indole compounds to treat medical disordersBDB
Achillion Pharmaceuticals
8
Amide compounds for treatment of immune and inflammatory disordersBDB
Achillion Pharmaceuticals
703
Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
101
Compounds for treatment of immune inflammatory disordersBDB
Achillion Pharmaceuticals
89
Amino compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
43
Ether compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
33
Phosphonate compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
698
Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disordersBDB
Achillion Pharmaceuticals
92
Alkyne compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
167
Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
116
Compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
43
Ether compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
16
Carbamate, ester, and ketone compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
33
Phosphonate compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
65
Amino compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals
2
Highly active nucleoside derivative for the treatment of HCVBDB
Achillion Pharmaceuticals
53
Amide compounds for treatment of complement mediated disordersBDB
Achillion Pharmaceuticals