BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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15 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
10
Structure-guided discovery of 2-aryl/pyridin-2-yl-1H-indole derivatives as potent and selective hepsin inhibitors.EBI
Aurigene Discovery Technologies
23
Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors.EBI
Aurigene Discovery Technologies
38
Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.EBI
Aurigene Discovery Technologies
14
Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors.EBI
Aurigene Discovery Technologies
18
Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.EBI
Aurigene Discovery Technologies
31
Design and synthesis of 2-substituted benzoxazoles as novel PTP1B inhibitors.EBI
Aurigene Discovery Technologies
15
Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action.EBI
Aurigene Discovery Technologies
25
Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies.EBI
Aurigene Discovery Technologies
96
Substituted imidazolidin-2-one derivatives as PRMT5 inhibitorsBDB
Aurigene Discovery Technologies
124
Imidazolidin-2-one compounds as PRMT5 modulatorsBDB
Aurigene Discovery Technologies
38
Substituted tetrahydroquinolinone compounds as ROR gamma modulatorsBDB
Aurigene Discovery Technologies
130
Pyrazolo[1,5-A][1,3,5]triazine and pyrazolo[1,5-A]pyrimidine derivatives as CDK inhibitorsBDB
Aurigene Discovery Technologies
89
Substituted heterocyclyl derivatives as CDK inhibitorsBDB
Aurigene Discovery Technologies
29
Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitorsBDB
Aurigene Discovery Technologies
46
Substituted pyrazole derivatives as selective CDK12/13 inhibitorsBDB
Aurigene Discovery Technologies